Effect of Risperidone on Polydipsia and Hyponatremia in Schizophrenia

Lee H.S. , Kwon K. , Alphs L.D. Effect of clozapine on psychogenic polydipsia in chronic schizophrenia. J Clin Psychopharmacol 1991; 11: 222–223.

Munn N. Resolution of polydipsia and hyponatremia in schizophrenic patients after clozapine treatment. J Clin Psychiatry 1993; 54: 439–440.

Gupta S. , Baker P. Clozapine treatment of polydipsia. Ann of Clin Psychiatry 1994; 6: 135–137.

de Leon J. , Verghese C. , Tracy J.I. Polydipsia and water intoxication in psychiatric patients: a review of the epidemiological literature. Biol Psychiatry 1994; 35: 408–419.

Illowsky B.P. , Kirch D.G. Polydipsia and hyponatremia in psychiatric patients. Am J Psychiatry 1988; 145: 675–83.

Brown R. An introduction to neuroendocrinology. Cambridge: University Press; 1994.

Kimura T. , Shoji M. , Itake K. The role of central alpha 1 -and alpha 2-adrenoreceptors in the regulation of vasopressin release and the cardiovascular system. Endocrinology 1984; 4: 1426–1432.

Zhao B. , Chapman C. , Brown D. Opioid-noradrenergic interactions in the neurohypophysis. Does noradrenaline mediate the actions of endogenous opioids on oxytocin and vasopressin release? Neuroendocrinology 1988; 48: 25–31.

Leysen J.E. , Gommeren W. , Eens A. Biochemical profile of risperidone, a new antipsychotic. J Pharmacol Exp Ther 1988; 247: 661–670

Coward D.M. General pharmacology of clozapine. B J Psychiatry 1992; 160(17 Suppl): 5S–11S.

Leibowitz S.F. Neurochemical systems of the hypothalamus: control of feeding and drinking behaviour and water-electrolyte excretion. In: Morgan P.J. , Panksepp J. , editors. Handbook of the hypothalamus, volume 3. New York: Marcel Dekker; 1980: 299–437.