The case is described of a patient with atypical affective disorder, episodic behavioural dyscontrol and parkinsonism resulting from presumed encephalitis lethargica. EEG abnormalities were found which were compatible with a post-encephalitic state and suggestive of epileptiform complications. Poor or deleterious response to neuroleptics, sleep disorder, and parkinsonism are features that may allow recognition of this illness in a psychiatric setting.
References
1.
von EconomoC.Encephalitis lethargica: its sequelae and treatment. Translation by NewmanKD. London: Oxford University Press, 1931.
2.
TimmeW.Acute epidemic encephalitis: an investigation by the Association for Research in Nervous and Mental Diseases. New York: Paul B. Hoeber, 1921.
3.
WardCD. Encephalitis lethargica and the development of neuropsychiatry. Psychiatr Clin North Am1986; 9(2): 215–224.
4.
HoenigJ, von AbbeyS.Economo's disease (encephalitis lethargica). Lessons for psychiatry. KurstakE, LipowskiZJ, MorozovPV, eds. In: Viruses, immunity and mental disorder. New York: Plenum Publishers, 1987.