A case is reported of a patient presenting to the psychiatric unit of our hospital with symptoms of depression and found to have an organic psychosis.
On routine SMA-12 investigation (12 channel auto analyzer), elevated serum calcium was detected on admission leading to the diagnosis of primary hyperparathyroidism (PHPT). The surgical removal of a parathyroid adenoma was followed by a rapid return of biochemical abnormalities to normal ranges. In spite of appropriate psychiatric management and fluctuations in the patient's clinical condition, the organic psychosis was unaltered and culminated in suicide 4 months after admission.
References
1.
PetersonP.Psychiatric disorders in primary hyperparathyroidism.J Clin Endocrinol Metab1968; 28: 1491–1495.
2.
KarpatiG., FrameB.Neuropsychiatric disorders in primary hyperparathyroidism.Arch Neurol1964; 10: 387–395.
3.
NobleP.Depressive illness and hyperparathyroidism.Proc Roy Soc Med1974; 67: 1066–1067.