This paper summarizes male/female contrasts and speculates on how they may influence onset age and outcome differences in schizophrenia.
References
1.
EllisL.Developmental androgen fluctuations and the five dimensions of mammalian sex (with emphasis upon the behavioral dimension and the human species).Ethology & SocioBiology1982; 3: 171–197.
2.
RischN., BaronM.X-linkage and genetic heterogeneity in bipolar-related major affective illness: re-analysis of linkage data.Am Hum Gen1982; 46: 153–166.
3.
GottesmanI., ShieldsJ.Schizophrenia: the epigenetic puzzle.New York: Cambridge University Press, 1982.
4.
Al-IssaI.Gender and psychopathology.New York: Academic Press, 1982.
5.
RoseR.M.Testosterone and aggression in man.Psychosom Med1974; 36: 467–468.
6.
CloningerC.R., ChristiansenK.O., ReichT., GottesmanI.I.Implications of sex differences in the prevalences of antisocial personality, alcoholism, and criminality for familial transmission.Arch Gen Psychiatry1978; 35: 941–951.
7.
CinaderB.Personal communication, 1984.
8.
DiPaoloT., PayetP., LabrieF.Effect of prolactin and estradiol on rat striatal dopamine receptors.Life Sciences1982; 31: 2921–2929.
9.
BédardP., BoucherR., DiPaoloT., LabrieF.Biphasic effect of estradiol and domperidone on lingual dyskinesia in monkeys.Exp Neurol1983; 82: 172–182.
10.
DiPaoloT., BédardP., LabrieF.Neuroleptic-like activity of estrogens. Proceedings of the VIIth World Congress of Psychiatry, Vienna, 1983, New York: Plenum Press, in press.
11.
SeemanM.V.Gender and the onset of schizophrenia: Neurohumoral influences.Psychiat J Univ Ottawa1981; 6: 136–138.
12.
HamiltonJ.A.The identity of post-partum psychosis in motherhood and mental Illness. In: BuckinghamI.F., KumarR., eds. London: Academic Press, 1982: 1–17.
13.
OsterP., ArabL., KohlmeierM., MordasiniR., SchellenbergB., SchlierfG.Effects of estrogen and progestogens on lipid metabolism.Am J Obstet Gynecol1982; 142: 773–775.
14.
AydF.J.Jr. Survey of drug-induced extrapyramidal reactions.JAMA1961; 175: 1054–1061.
15.
SmithJ.M., DunnD.D.Sex differences in the prevalence of severe tardive dyskinesia.Am J Psychiatry1979; 136: 1080–1082.
16.
MacLuskyN.J., NaftolinF.Sexual differentiation of the central nervous system.Science1981; 211: 1294–1303.
17.
Durden-SmithJ., de SimoneD.Sex and the brain.New York: Arbor House, 1983.
18.
RainbowT.C., ParsonsB., McEwenB.S.Sex differences in rat brain oestrogen and progestin receptors.Nature1982; 300: 648–649.
19.
AyoubD.M., GreenoughW.T., JuraskaJ.M.Sex differences in dendritic structure in the preoptic area of the juvenile macaque monkey brain.Science1983; 219: 197–198.
20.
FischetteC.T., BiegonA., McEwenB.S.Sex differences in serotonin I: receptor binding in rat brain.Science1983; 222: 333–335.
21.
LuineV.N., McEwenB.S.Sex differences in cholinergic enzymes of diagonal band nuclei in the rat preoptic area.Neuroendocrin1983; 36: 475–482.
22.
McGloneJ.Sex differences in human brain asymmetry: a critical survey.Behav & Brain Sciences1980; 3: 215–263.
23.
HauserP., PollockB., FinkelbergF., McGrailS., VoineskosG., SeemanM.V.Brain plasticity: a possible protective factor in schizophrenia. Submitted, Br J Psychiatry.
24.
Erlenmeyer-KimlingE. In: FennH.A., NasrallahH.A., eds. Schizophrenia as a brain disease.New York: Oxford University Press, 1982.
25.
SartoriusN.World Health Organization: schizophrenia: an international follow-up study.Chichester: John Wiley, 1979.
26.
WattN.F.Patterns of childhood and social development in adult schizophrenia.Arch Gen Psychiatry1978; 35: 160–165.
27.
BusfieldJ.Gender and mental illness.Int J Ment Health1982; 11: 46–66.
28.
McDermottJ.F., RobillardA.B., CharW.F., HsuJ., TsengW.S., AshtonG.C.Reexamining the concept of adolescence: differences between adolescent boys and girls in the context of their families.Am J Psychiatry1983; 140: 1318–1322.
29.
SeemanM.V.Schizophrenic men and women require different treatment programs.J Psychiat Treatment & Eval1983; 5: 143–148.
30.
KeskinerA., ZalemanJ., RuppertE.H.Advantages of being female in psychiatric rehabilitation.Arch Gen Psychiatry1973; 28: 689–692.
31.
SalokangasR.K.R.Prognostic implications of the sex of schizophrenic patients.Br J Psychiatry1983; 142: 145–151.
32.
TestM.A., BerlinS.B.Issues of special concern to chronically mentally ill women.Prof Psychol1981; 12: 136–145.
33.
RoyA.Suicide in chronic schizophrenia.Br J Psychiatry1982; 141: 171–177.
34.
TsuangM.T., WoolsonR.F.Excess mortality in schizophrenia and affective disorder.Arch Gen Psychiatry1978; 35: 1181–1185.