An approach to the management of the behavioural manifestations of Wilson's Disease by operant technique is outlined. There was considerable improvement in the patient's ability to perform autonomously on this program. When the contingencies were changed the patient's behaviour deteriorated markedly, thereby suggesting that improvement in behaviour was not due to medication alone.
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KnehrC.A., BearnA.G.: Psychological impairment in Wilson's Disease.J Nerv Merit Dis, 124(3): 251–255, 1956.