Evaluation Des Effets Secondaires Chez Les Nevrotiques - Un Essai Avec La Mesoridazine † : Et Le Placebo

Abstract

The incidence of side effects following administration of mésoridazine and placebo was studied in a neurotic outpatient population using an open questionnaire and a symptom check-list. Men on mésoridazine reported more side effects with a symptom check-list than on the questionnaire. This difference was not significant in women. More symptoms were elicited with a check-list while the patients were on the drug than by questioning. These side effects were mainly gastro-intestinal and were mild. Cardio-vascular symptoms were as frequent on placebo as on the active drug. After six weeks of double-blind administration there was no difference in the total number of side effects reported for placebo and for mésoridazine.