Yesterday,Today and Tomorrow a Point of View

Baastrup P. C. and Schou M. : Lithium as a prophylactic agent. Its effect against recurrent depressions and manic-depressive psychosis. Arch. Gen. Psychiatry 16, 162-172, 1967.

Baastrup P. C. , Poulsen J. C. , Schou M. : Prophylactic lithium: double-blind discontinuation in manic depressive and recurrent depressive disorders. Lancet ii, 326-330, 1970.

Blackwell B. and Shepherd M. : Prophylactic lithium: another therapeutic myth? Lancet i, 968-971, 1968.

Braithwaite R. A. , Goulding R. , Theano G. , Bailey J. and Coppen A. : Clinical significance of plasma levels of tricyclic antidepressant drugs in the treatment of depression. Lancet i, 556-557, 1973.

Bunney W. E. Jr. , Janowsky D. S. , Goodwin F. K. , Davis J. M. , Brodie H. K. H. , Murphy D. L. and Chase T. N. : Effect of L-dopa on depression. Lancet i, 885-886, 1969.

Bunney W. E. Jr. , Brodie H. K. H. , Murphy D. L. and Goodwin F. K. : Studies of alpha-methylparatyrosine, L-dopa and L-tryptophan in depression and mania. Am. J. Psychiatry 127, 872-881, 1971.

Burrows G. D. , Davies B. and Scoggins B. A. : Plasma concentration of nortriptyline and clinical response in depressive illness. Lancet ii, 619-623, 1972.

Cade J. F. J. : Lithium salts in the treatment of psychotic excitement. Med. J. Aust. 36, 349-352, 1949.

Carl-Gustaf H. and Holmstedt B. : Mass fragmentography. Identification of chlorpromazine and its metabolites in human blood by a new method. Analytical Biochemistry 25, 532-548, 1968.

Coppen A. : The Biochemistry of affective disorders. Br. J. Psychiatry 113, 1237-1264, 1967.

Coppen A. J. , Shaw D. M. , and Farrell J. P. : Potentiation of the antidepressive effect of a monoamine-oxidase inhibitor by tryptophan. Lancet ii, 79-81, 1963.

Curry S. H. and Brodie B. B. : Estimation of nanogram quantities of chlorpromazine in plasma using gas-liquid chromatography with an electron capture detector. Fed. Proc. 26, 761, 1967.

Fawcett J. and Sconiopoulos V. : Dextroamphetamine response as a possible predictor of improvement with tricyclic therapy in depression. Arch. Gen. Psychiatry 25, 247-255, 1971.

Gjessing L. R. : A review of the biochemistry of periodic catatonia. Proceedings of the 4th World Congress of Psychiatry, Madrid September 5-11, 1966. Excerpta Medica International Congress Series No. 150, pp. 516–522.

Goodwin F. K. , Murphy D. L. , Brodie H. K. H. and Bunney W. E. Jr. : L-dopa, catecholamines and behaviour. A clinical and biochemical study in depressed patients. Biol. Psychiatry 2, 341-366, 1970.

Haider I. : Single daily dose of a new form of amitriptyline in depressive illness. Br. J. Psychiatry 120, 521, 1972.

Hoffer A. : Schizophrenia and diet. Address delivered to the Ontario Chapter, Canadian Health Food Dealers National Association, Inn on the Park, Toronto, March 14, 1973.

Hoffer A. , Osmond H. , Callbeck M. and Kahan I. : Treatment of schizophrenia with nocotine acid and nicotinamide. J. Clin. Exptl. Psychopath. 18, 131-158, 1957.

Kedward H. B. , Eastwood M. R. , Allodi F. , Duckworth G. S. : The Chronic Psychiatric Hospital Population over the Past Decade: Trends and Meanings. Paper presented at the Canadian Psychiatric Association Annual Meeting in Vancouver, June 21, 1973.

Kragh-Sorensen P. , Asberg M. and Eggert-Hansen C. : Plasma-nortriptyline levels in endogenous depression. Lancet 1, 113-115, 1973.

Maas J. W. , Fawcett J. A. and Dekirmenjian H. : Catecholamine metabolism, depressive illness and drug response. Arch. Gen. Psychiatry 26, 252-262, 1972.

Mindham R. H. S. , Howland C. and Shepherd M. : An evaluation of continuation therapy with tricyclic antidepressants in depressive illness. Psychol. Med. 3, 5-17, 1973.

Morrison L. , Clancy J. , Crowe R. and Winokur G. : The IOWA 500: I. Diagnostic vaildity in mania, depression and schizophrenia. Arch. Gen. Psychiatry 27, 457-461, 1972.

Mosher L. R. : Nicotinic acid side effects and toxicity: A Review. Am. J. Psychiatry 126, 1290-1296, 1970.

Overall J. E. , Hollister L. E. , Meyer F. , Kimball I. , Jr. and Shelton J. : Imipramine and thioridazine in depressed and schizophrenic patients. Are there specific drugs? J.A.M.A. 189, 605-608, 1964.

Pare C. M. B. : Potentiation of a monoamine oxidase inhibitor by tryptophan. Lancet ii, 527-528, 1963.

Pare C. M. B. and Mack J. W. : Differentiation of two genetically specific types of depression by the response to antidepressant drugs. Journal of Med. Genet 8, 306-309, 1971.

Prange A. J. , Wilson I. C. , Knox A. E. , McClane T. K. , Breese G. R. , Martin B. R. , Alltop L. B. , and Lipton M. A. : Thyroid-imipramine clinical and chemical interaction: Evidence for a receptor deficit in depression. J. Psychiatr. Res. 9, 187-205, 1972.

Prien R. F. , Caffey E. M. Jr. , Klett C. J. : Comparison of lithium carbonate and chlorpromazine in the treatment of mania. Arch. Gen. Psychiatry 26, 146-153, 1972.

Prien R. F. , Caffey E. M. Jr. , Klett C. J. : A comparison of lithium carbonate and chlorpromazine in the treatment of excited schizoaffectives. Arch. Gen. Psychiatry 27, 182-189, 1972.

Sandler M. : Role of 5-HT in Mental Diseases. At International Symposium on 5-Hydroxytryptamine and other Indole-alkylamines in Brain. Cagliari, Italy, May 27-June 2, 1973.

Schildkraut J. J. : The catecholamine hypothesis of affective disorders: a review of the supporting evidence. Am. J. Psychiatry 122, 509-522, 1965.

Schildkraut J. J. , Draskoczy P. R. , Gershon E. S. , Reich P. and Grab E. L. : Catecholamine metabolism in affective disorders. IV. Preliminary studies of norepinephrine metabolism in depressed patients treated with amitriptyline. J. Psychiatr. Res. 9, 173-185, 1972.

Szara S. , Axelrod J. and Perlin S. : Is andrenochrome present in the blood? Am. J. Psychiatry 115, 162-163, 1958.

Tanghe A. and Vereecken J. L. Th. M. : fluspirilene, an injectable, and penfluridol, an oral long-acting, neuroleptic. Acta Psychiatr. Scand. 48, 315-331, 1972.

The Canadian Foundation for the Advancement of Therapeutics, 1199 Seymour Avenue, Montreal 108, P.Q.

van Praag H. M. and Korf J. : 4-chloramphetamines. Chance and trend in the development of new antidepressants. J. Clin. Pharmacol. 13, 3-14, 1973.

Winokur G. , Morrison J. , Clancy J. and Crowe R. : The IOWA 500: A blind family history comparison of mania, Depression and Schizophrenia. Arch. Gen. Psychiatry 27, 462-464, 1972.