Abstract
The effects of azocyclonol hydrochloride were tested on 19 carefully selected patients. Results were completely negative, no evidence being found for this drug's alleged antihallucinatory, anticonfusional, antidelusional role.
The literature on this drug was reviewed, and possible reasons for the discrepancies as to results were suggested.
The allegedly “Model Psychoses” are not the same as schizophrenia, but are rather toxic psychoses. Blocking effects on them, though interesting, are not necessarily an open door to the treatment of schizophrenia.
The importance of attempting to control all the known factors involved in the curative process in psychiatry, in doing drug research, is stressed. This must include the role of psychological factors which is too often ignored.