Abstract
Objective
To examine the impact of the COVID-19 pandemic on first year undergraduate student mental health.
Methods
As part of the Queen’s University
Results
Clinically significant symptoms of depression, anxiety, insomnia, and self-harm were reported more frequently in the 2020–2021 cohort, coincident with remote learning and pandemic restrictions. In female students, screen positive rates for anxiety and depression, and suicidal ideation increased from about one-third to just under one-half in association with the pandemic (χ2,
Conclusions
Mental health concerns including anxiety, depression and sleep problems increased in first year students during the pandemic, especially among females, while alcohol use declined. These findings highlight the negative mental health impact associated with studying under pandemic restrictions involving remote learning and social distancing.
Introduction
Entry to university marks an important developmental period for young people. At this stage, most students are tasked with leaving home, making new friends, being more autonomous, navigating new learning environments and health care services, and acquiring study skills to meet higher education standards. 1 This key period for psychological and sociological development coincides with a time of accelerated brain development 2 and the peak period of risk for the onset of major mental disorders. 3 Further, university students have to navigate important lifestyle decisions (i.e., drug and alcohol use, exercise and sleep regulation) in the face of varying abilities to cope in healthy ways, which contributes to their overall well-being. It is therefore not surprising that universities in Canada,4,5 as in other countries, 6 continue to experience a high demand for student mental health support.
Restrictions related to the COVID-19 pandemic posed additional challenges for university students. 7 During its first and second waves, Canadian university campuses were physically closed to most students, and teaching methods shifted to online formats.8,9 In-person socialization was suspended, and remote learning which included asynchronous pre-recorded lectures increased the demand on students for self-regulation and time management. Many students lost a degree of autonomy as they were required to study from home, sometimes under suboptimal circumstances (e.g., due to lack of study space, and family/housemate relationships). 7 However, there are only sparse data to describe the impact of these pandemic-related changes on the mental health of university students studying in Canada.
The
The existence of
We hypothesized that while clinically significant symptoms of common mental health concerns would continue to be highly prevalent over time, screen positive rates at school entry and over the first year would be increased in students studying under pandemic conditions, while substance use and other behaviours traditionally related to socializing in-person would remain unchanged or become less prevalent.
Methods
Setting
Queen’s University is in Kingston, Ontario, Canada; a small city of approximately 500,000 located between the major centres of Toronto, Montreal, and Ottawa. Queen’s is a medium-sized, publicly funded university that accepts approximately 4,500 undergraduate students annually. In the fall of 2019, 90% of first-year students were 18 years or younger on the first day of school and 73% attended high school in Ontario. 11 Prior to pandemic related restrictions, more than 90% of first-year students lived in residence on campus. 12
Data Source
As described elsewhere, first year undergraduate students at Queen’s University were invited to complete an online mental health survey at the start of the fall term (September) and end of the spring term prior to final exams (in March) as part of the U-Flourish study. 10 Three successive cohorts of students entering university for the academic years of 2018–2019 (Cohort 1; pre-pandemic), 2019–2020 (Cohort 2; transitional), and 2020–2021 (Cohort 3; during pandemic) contributed. Validated measures were used to assess mental health outcomes, with supplemental information about the student experience gathered via free text responses. All student participants read a letter of information and provided informed consent prior to completing the survey. 10
Through a student-designed and led engagement campaign, almost 60% of eligible students completed the baseline fall survey in 2018 4 ; a response rate replicated in 2019. In 2020, the response rate for the baseline survey dropped to 23%, at a time when the university had shifted to an online format and in-person engagement activities were not possible. Response rates to the follow-up survey in successive cohorts were 64% in the 2018 cohort, then dropped to 37% and 37% in 2019 and 2020, respectively.
The COVID-19 pandemic was officially declared in Canada in March of 2020. 13 Hence, students enrolled in the 2019–2020 cohort were exposed to the restrictions related to the pandemic including campus closure and online proctored examinations only during the very end of their academic year, while the 2020–2021 cohort studied under pandemic conditions for their entire academic year. This meant that the campus was closed, and most curriculum was offered remotely through a mixture of online synchronous and asynchronous formats and examinations were remotely proctored.
Study Variables
Measures of mental health, well-being, and associated risk and protective factors considered in the U-Flourish survey have been described in detail elsewhere.4,10 A brief synopsis follows.
Demographics
Students reported their age in years, gender, international/domestic student status, ethnicity, and the highest level of education completed by their parents. Individual programs of study were obtained from the university administrative database.
Diagnosed Mental Illness
Students reported whether they (personal history) and any of their first-degree relatives (family history) had ever been diagnosed with any of the following mental disorders: mood, anxiety, psychotic, eating, sleep, neurodevelopmental, and substance use.
Childhood exposures to risk
The survey included questions from the Childhood Experience of Care and Abuse Questionnaire (CECA) 14 to ascertain a self-reported history of physical abuse, sexual abuse, and bullying by peers during childhood.
Mental Health Treatment
Students indicated whether they were currently receiving treatment or support for a mental health concern, and in Cohorts 2 and 3 students also reported on their lifetime history of mental health treatment at baseline.
Symptoms of Common Mental Illnesses
Current symptoms of depression were measured using the 9-item Patient Health Questionnaire (PHQ-9). 15 Responses to the items were summed (range = 0–27), with a score of ≥ 10 indicating a “screen positive” or clinically significant depressive symptoms. 15 Current symptoms of anxiety were measured using the Generalized Anxiety Disorder 7-item scale (GAD-7). 16 Responses to the items were summed (range = 0–21), with a score of ≥ 10 indicating a screen positive or clinically significant anxiety symptoms. 16 Lifetime history of self-harm, suicide ideation, and suicide attempts were measured using questions from the Columbia Suicide Rating Scale. 17 Sleep problems were assessed using the 8-item Sleep Condition Indicator (SCI-8). 18 Responses to the items were summed with a score of ≤ 16 out of 32 indicating reduced sleep quality and clinically significant symptoms of insomnia. 18 Person-mean imputation was used to calculate scale scores if one item was missing.
Substance Use
Past month frequency of alcohol consumption, binge drinking (5 + alcoholic drinks on one occasion) and cannabis use (“weekly or more” vs. “less than weekly”) was reported. The number of drinks containing alcohol consumed on a typical day when the student was drinking was grouped as “5 or more” versus “less than 5.” Illicit drug use in the past month, was based on the use of any of the following: cocaine (coke, crack, etc.), other street drugs (e.g., opioids, LSD, speed, MDMA, ecstasy), or a prescription drug without a prescription or to get “high, buzzed or numbed out.”
COVID-19 Impact (Cohort 3; 2020–2021)
Eleven items assessing the perceived impact of the pandemic and associated social distancing and remote learning, developed in collaboration with student partners, were added to the follow-up survey for Cohort 3. Students rated the impact on their university experience, including perceptions of remote learning, social relationships, leisure activities, and finances on a 5-point scale from 1 = “Very negative” to 5 = “Very positive.”
19
In addition, in both the baseline and follow-up surveys, students in Cohort 3 provided free text responses to the open-ended question “
Analysis
All analyses were conducted using SAS Version 9.4 (
Prevalence levels and associated 95% confidence intervals for the mental health outcomes reported at school entry were described in each propensity score-matched cohort. All analyses were stratified by male or female gender; reports from non-binary students were excluded due to small cell sizes and associated privacy concerns. Significant differences in prevalence between cohorts were estimated via chi-square tests. In a planned sensitivity analysis, we examined relationships between cohort membership and mental health outcomes using all available data. Relative Risks were estimated via multivariable log-binomial regression models, with adjustment for the variables included in the propensity score-matched analysis.
Ethics
The U-Flourish study followed the ethical principles set-out in the Declaration of Helsinki and was approved for ethical compliance by the Queen’s University and Affiliated Teaching Hospitals Research Ethics Board (HSREB PSIY-609-18).
Results
Characteristics of the propensity-matched samples used to compare mental health outcomes at university entry are presented in Table 1. The matched cohorts were similar with respect to all key variables examined. Specifically, at entry to university student participants were mainly between 18 and 19 years old, two-thirds were female, and most were domestic students of White or Asian ethnicity, who had parents with higher education backgrounds. The leading programs of study were the Arts, Humanities and Social Sciences, followed by Life and Physical Sciences, and Engineering. About one in four students reported a lifetime history of a diagnosed mental disorder and 40% reported an immediate family member with a lifetime mental disorder. Specifically, at university entry, approximately one in seven students reported a lifetime history of a mood disorder (13.2–15.4% across cohorts). In terms of major risk factors, about one in five students reported physical or sexual abuse during childhood. Further, over one-fifth of students entering university reported a lifetime history of treatment for a mental health concern; and the rate of current mental health treatment at university entry was: 10.8%, 9.3%, and 14.1% across Cohorts 1–3, respectively.
Description of the Propensity Matched Samples of First Year Undergraduate Students at University Entry Across Successive Cohorts.

Prevalence (95% confidence interval) of clinically significant depressive and anxiety symptoms, insomnia, lifetime self-harm, alcohol consumption, and cannabis use at school entry across successive cohorts, in female and male students.
Screen Positive Rates of Reported Mental Health Symptoms and Substance use in Successive Propensity Matched Samples of First Year Undergraduate Students at Entry to University Before (Fall 2018 and Fall 2019) and During (Fall 2020) the Pandemic (%), by Gender.
Changes in the Prevalence of Mental Health and Substance use Outcomes in Undergraduate Students Over the First Year of University in Cohort 1 (2018–2019; Pre-Pandemic) and Cohort 3 (2020–2021; During Pandemic), and Risk of Mental Health and Substance Use Outcomes at the end of First Year in Cohort 3 Compared to Cohort 1.
Although not statistically significant, students in Cohort 3 appeared to be at increased risk of self-harm and suicide ideation over the academic year (Table 3). Self-harm over the past 6 months was reported by 6.7% of female and 3.9% of male students in Cohort 1 compared to 11.9% and 6.1% in Cohort 3. Suicide ideation increased from 14.8% to 25.2% in females, and from 12.8% to 17.4% in males. Cohort membership was not significantly associated with risk of a suicide attempt, which was reported by a small proportion of students in both cohorts. In students studying under pre-pandemic conditions, 18 (1.6%) females and 6 (1.5%) males reported having made a suicide attempt over the past 6 months, compared to 4 (1.4%) females and 4 (3.5%) males studying under pandemic conditions. Finally, contrary to the previous findings, during the pandemic both male and female students were significantly less likely to report weekly alcohol consumption at follow-up. There was also a non-significant decrease in cannabis use at follow-up in the pandemic compared to pre-pandemic cohort, in both males and females.

Impact of the COVID-19 pandemic and associated social distancing and remote learning on your...
Following these items, students had the opportunity to voice any other specific impacts of the pandemic on their mental health, wellbeing, or education. Major themes identified from the open-text responses (
Discussion
We compared three successive cohorts of first-year undergraduate students to examine the impact of the COVID-19 pandemic on student mental health at entry to university and over the first academic year. The main findings included a sustained high level of clinically significant symptoms of common mental health concerns at entry to university, which were elevated in students studying under pandemic conditions. Specifically, screen-positive levels of self-reported depressive, anxiety, and insomnia symptoms, and self-harm were significantly higher among students who entered university during the pandemic compared to those entering the year prior. Observed increases were greatest amongst females, nearly half of whom met screening thresholds for at least one mental health outcome upon entry to university during the pandemic. While screen-positives increased over the academic year before and during the pandemic, there appeared to be a greater increase in female students studying under pandemic conditions, particularly for symptoms of anxiety. Conversely, reported levels of problematic substance use (alcohol binging and/or regular recreational drug use) were lower during the pandemic, consistent with reductions in alcohol consumption reported among young adults in Canada,21,22 associated with decreases in social gatherings and COVID-related restrictions. 21 Students indicated that the pandemic had negatively impacted their lives and university studies and shared concerns around reduced social and school connectedness, the quality of their learning experience and specifically remote learning, as well as concerns about future academic and career prospects.
The potential impacts of the COVID-19 pandemic on student mental health have been reported in Canada23,24 and globally, although many of these studies are limited in sample size and scope of enquiry, and the findings vary by educational setting and geographic context. At Carleton University the pandemic has had a negative effect on undergraduate student stress levels and mental health, especially among females. 23 Copeland et al. 25 reported modest increases in externalizing symptoms and attention problems at the onset of the pandemic in students at the University of Vermont (UVM), with evidence of a protective effect of having been enrolled in a Wellness program; while internalizing symptoms remained stable. In a broader sample of US college students, Conrad et al. 9 documented increases in symptoms of grief, loneliness, and generalized anxiety with the onset of the pandemic, which were especially pronounced in students required to vacate campus residences and other forms of university housing. Increases in anxiety and stress were documented in first-year French students during the pandemic lockdown, but particularly amongst those who did not relocate to live with family. 26 In a study of Swiss undergraduates, levels of anxiety, depression, stress, and loneliness increased during the pandemic. 27 In an exploratory analysis, social isolation and lack of emotional support were associated with worse mental health outcomes. Evans et al. 28 compared 254 UK undergraduate psychology students in pre-pandemic versus “lockdown” conditions, and documented significant increases in some symptoms (e.g., depression), reductions in others (wellbeing, alcohol use), and no change in symptoms of anxiety, loneliness, or sleep quality. Toth et al. 29 reported findings more consistent with our own, with elevated levels of depression and anxiety in pandemic versus non-pandemic student samples. Similarly, Canadian students with no pre-existing mental health problems reported increases in psychological distress during the pandemic. 24 Finally, a major study of medical students in China reported that up to one-quarter of participants experienced mild to severe symptoms of anxiety associated with worries about academic delays and financial issues. 30
A significant proportion of students in our study reported that the pandemic and associated restrictions had negatively impacted their social life and ability to connect with friends, their university studies, including concerns about the quality of online learning and their grades, their ability to participate in exercise and leisure activities, and their future prospects and finances. In keeping with these quantitative findings, students shared that the pandemic and associated restrictions had negatively impacted their mental health through heightened feelings of stress, anxiety, and hopelessness. Difficulty with time management, blurred work-life boundaries, perceived lower quality of online learning, and inadequate academic support were commonly expressed academic challenges. Pandemic-related public health restrictions resulted in students feeling socially isolated from friends and disconnected from the campus community. General concerns about the future, including job prospects and whether a “return to normal” would occur, were common sources of distress. Established wellness, coping, and lifestyle-enriching activities were disrupted due to the reduction of available recreational and meeting spaces, as well as the emphasis on physical distancing. The emergence of novel or worsening eating, sleep, and substance use problems were described and, in some cases, considered to be a direct effect of COVID-19-related changes.
Study findings have several important clinical implications. First, we found evidence of a significant degree of adversity experienced by first-year undergraduate students related to the pandemic, and a substantial negative impact on student mental health. While this finding is not surprising given the emerging literature, it underscores the scope of need in terms of planning for university student mental health support. Reported increases in clinically significant levels of mental health problems will inevitably increase the already high student demand for support. Moreover, while reports of some mental health concerns (e.g., recreational drug use, alcohol misuse) declined, this trend is expected to be temporary as it had more to do with the lack of opportunity to socialize with peers. Therefore, a student-tailored and accessible clinical triage system with therapeutic benefit from the first contact and that maps student need to the appropriate level of support seems a priority. 5
Future studies are needed to examine the underlying associations and mechanisms driving mental health outcomes and to assess sustained effects of the pandemic on the mental health burden and academic experiences of postsecondary students. Given the sustained and increasing need for student mental health support, optimization of models guiding the provision of services is required in collaboration with students, along with testing in accordance with evidence-based principles. For example, both universal health promotion and targeted interventions organized in an integrated stepped care model have been proposed, but as yet not rigorously studied.5,32
Conclusion
We found evidence that the COVID-19 pandemic was associated with a significant increase in mental health concerns in first year undergraduate students, especially among females. Students studying under pandemic conditions expressed feeling isolated from peers, a lack of membership with the university, reduced quality of their educational experience, limited recreational outlets and future academic and career uncertainty. These findings address the identified need for large-scale longitudinal data to inform the mental health burden in undergraduate students and underscore the substantial need in terms of university student mental health support. Future research on the sustained effects of the pandemic and underlying mechanisms is needed to inform evidence-based prevention and early intervention efforts.
Supplemental Material
sj-pdf-1-cpa-10.1177_07067437221094549 - Supplemental material for The Impact of the COVID-19 Pandemic on the Mental Health of First-Year Undergraduate Students Studying at a Major Canadian University: A Successive Cohort Study
Supplemental material, sj-pdf-1-cpa-10.1177_07067437221094549 for The Impact of the COVID-19 Pandemic on the Mental Health of First-Year Undergraduate Students Studying at a Major Canadian University: A Successive Cohort Study by Nathan King, PhD, William Pickett, PhD, Daniel Rivera, BSc, Jin Byun, Melanie Li, Simone Cunningham, PhD, and Anne Duffy, MD, FRCPC in The Canadian Journal of Psychiatry
Footnotes
Acknowledgments
We thank the students who “had their say” and participated in this research and the student volunteers who helped develop and raise awareness contributing to the high participation rate.
Data Access
Access to de-identified data will be considered upon request to the corresponding author after study completion.
Declaration of Conflicting Interests
The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Funding
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Canadian Institutes of Health Research (grant no. 165597) and the Rossy Family Foundation.
Supplemental Material
Supplemental material for this article is available online.
References
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