Are Antidepressants as Effective as Claimed? Yes,but …

Health Canada. A report on mental illnesses in Canada [Internet]. Ottawa (ON): Health Canada; 2002. [modified 2002 Oct 15; cited 2006 Nov 28]. Available from: http://www.phac-aspc.gc.ca/publicat/miic-mmac/.

Davidson JR Meltzer-Brody SE . The underrecognition and undertreatment of depression: What is the depth and breadth of the problem? J Clin Psychiatry. 1999;60(Suppl 7):4–9.

Moncrieff J Cohen D. Do antidepressants cure or create abnormal brain states? PLoS Med. 2006;3(7):e240.

Duman RS Monteggia LM . A neurotrophic model for stress-related mood disorders. Biological Psychiatry. 2006;59(12):1116–1127.

MacQueen GM Campbell S McEwen BS , Course of illness, hippocampal function, and hippocampal volume in major depression. Proc Natl Acad Sci U S A. 2003;100(3):1387–1392.

Gualtieri CT Johnson LG Benedict KB . Neurocognition in depression: Patients on and off medication versus healthy comparison subjects. J Neuropsychiatry Clin Neurosc. 2006;18(2):217–225.

Mayberg HS Liotti M Brannan SK , Reciprocal limbic-cortical function and negative mood: Converging PET findings in depression and normal sadness. Am J Psychiatry. 1999;156(5):675–682.

Kennedy SH Evans KR Kruger S , Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. Am J Psychiatry. 2001;158(6):899–905.

Mayberg HS Silva JA Brannan SK , The functional neuroanatomy of the placebo effect. Am J Psychiatry. 2002;159(5):728–737.

McGrath PJ Stewart JW Fava M , Tranylcypromine versus venlafaxine plus mirtazapine following three failed antidepressant medication trials for depression: A STAR*D report. Am J Psychiatry. 2006;163(9):1531–1541.

Dewa CS Hoch JS Lin E , (2003) Pattern of antidepressant use and duration of depression-related absence from work. Br J Psychiatry. 2003;183:507–513.

Rost K Smith JL Dickinson M. The effect of improving primary care depression management on employee absenteeism and productivity. A randomized trial. Med Care. 2004;42(12):1202–1210.

Kocsis JH Schatzberg A Rush AJ , Psychosocial outcomes following long-term, double-blind treatment of chronic depression with sertraline vs placebo. Arch Gen Psychiatry. 2002;59(8):723–728.