Treatment of La Peyronie's disease with Verapamil and cryoelectrophoresis

Abstract

Over the years the treatment of induratio penis plastica has known many ups and downs, using many drugs administered in different ways (Potaba, vit. E, Nimesulide, Orgotein) associated or not with other drugs (Potassium iodide, Cortisone). Verapamil has been used in the last two years. It is a calcium antagonist drug commonly used by cardiologists in treating arrhythmia. It is administered by injection directly into the plaque at a dose of 5 mg a week and has given good results with regard to pain and curvature of the shaft during erection. We treated 40 patients from 1995 to 1997, 13 with injection into the plaque and 27 with a new method of drug transportation called cryoelectrophoresis. The physical principles of this method are referred to and the authors’ experience and results of IPP treatment are described.