From January 1992 to May 1996, we performed 526 prostatic biopsies for suspected carcinoma after digital rectal examination (DRE), transrectal ultrasonography (TRUS) and PSA. 288 patients underwent transperineal echo-guided biopsy (TP) and 238 transrectal biopsy (TR). Diagnosis of prostatic cancer was made in 133 cases: 69 in the TP group and 64 in the TR group. We evaluated the reliability, sensitivity, specificity and complications of the two methods. TR biopsy is simple to do and well-tolerated by the patient, but has a greater number of complications.
CoonerW.H.: Prostate specific antigen, digital rectal examination, and transrectal ultrasonic examination of the prostate in prostate cancer detection. Monogr. Urol., 12: 3–13, 1991.
2.
CoonerW.H.: Rectal examination and ultrasonography in the diagnosis of prostate cancer. Prostate, 4: 10, 1992.
3.
HodgeK.K., McNealJ.E., TerrisM.K.: Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J. Urol., 142: 71–75, 1989.
4.
FontanaD.: Confronto tra mapping prostatico ecoguidato e digitoguidato. Atti 68° Congresso SIU. Roma, 2–5 luglio 1995.
5.
TerrisM.K., McNealJ.E., StameyT.A.: Detection of clinically significant prostate cancer by transrectal ultrasound guided system biopsies. J. Urol., 148: 829–832, 1992.
6.
CoonerW.K.: Prostate specific antigen coordinated with digital examination and transrectal ultrasonography in the detection of prostate cancer. World J. Urol., 11: 215, 1993.
7.
BensonM.C.: Prostate specific antigen density: a means of distinguishing BPH and prostate cancer. J. Urol., 147: 815–6, 1992.
8.
StameyT.: PSA as a serum marker for the adenocarcinoma of the prostate. N. Engl. J. Med., 31: 909, 1989.
9.
HudsonM.A., CatalonaW.J.: Clinical use of PSA in patients with prostate cancer. J. Urol., 142: 1011–17, 1989.
HastakS.M.: Ultrasonically guided transperineal in the diagnosis of prostatic carcinoma. J. Urol., 128: 69, 1982.
13.
LiddelT.H., McDougalW.S., BurksD.D.: Ultrasound versus digitally directed prostatic needle biopsy. J. Urol., 135: 716, 1986.
14.
SimpsonK.N., BrownR.E.: Cost effectiveness of adding prostate specific antigen (PSA) test to digital examination (ORE) for early detection of prostate cancer. J. Urol., 149 Suppl: 413A, 1993.
