Abstract
In an open randomised three-branch study without placebo control, an attempt was made to form a hypothesis regarding the most effective medical treatment of benign prostatic hyperplasia (BPH). 195 patients were enrolled in the study according to precise criteria of eligibility and were evaluated after 6 months both subjectively (IPSS) and objectively (urodynamic study). 53 were treated with finasteride, 45 with alfuzosin and 49 with an association of the two drugs. A statistically significant improvement was noted in the main urodynamic parameters (B better than C and C better than A), clinical evaluation revealed a positive overall influence of the treatments on the IPSS without specific correlations with obstruction urodynamic parameters, which although showing improvement mostly remained at a pathological level.
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