The Contralateral Testis in Cryptorchid Patients

Abstract

We performed bilateral testicular Fine Needle Aspiration Cytology (FNAC) in a large group of unilateral cryptorchid subjects to characterize the tubular status related to the seminal pattern. In azoospermic and in severe oligozoospermic subjects the cytological picture of the contralateral testis showed similar lesions to those observed in the cryptorchid testis, while in moderate oligozoospermic subjects this analysis revealed the presence of a normal spermatogenic line and in normospermic subjects the presence of a compensatory activity of the tubular function. In conclusion, in unilateral cryptorchidism a frequent testicular damage in the orchidopexied testis and a concomitant tubular alteration in the contralateral scrotal testis exist, suggesting that cryptorchidism is the end point of different pathological conditions, including intrinsic (congenital) and extrinsic (anatomical) causes. FNAC of both testes could represent a tool for the clinician in the assessment of the tubular status in cryptorchid subjects, above all in presence of azoospermia or severe oligozoospermia. In these cases the existence of intratesticular spermatids or mature spermatozoa allows new assisted reproduction techniques using intratesticular germ cells to be used.