— The Authors report their experience on early cancer lesions of the prostate: atypical adenomatous hyerplasia and intra-epithelial tumour. Even though such lesions could develop long-term into a prostatic tumour, the Authors do not justify handling and treating such patients as affected by prostatic tumour. Nevertheless, strict patient follow-up is useful, including rectal examination and PSA testing every 3 months and transrectal prostatic sonography with cytological testing or gland biopsy every 6 months.
Mc NealJ.E.: The prostate gland: morphology and pathology. Monogr. Urol., 4: 3, 1983.
2.
McNealJ.E., RedwineE.A., FreihaF.S., StameyT.A.: Zonal distribution of prostatic adenocarcinoma: correlation with histologic pattern and direction of spread. Am. J. Surg. Pathol., 12: 897, 1988.
3.
P.O.N.CA.P. (Progetto Obiettivo Nazionale Carcinoma Prostatico), 1988.
4.
BostwickD.C., SrigleyJ.R.: Premalignant lesions. In: BostwickD.C. (ed.): Pathology of prostate. Churchill Livingstone; New York, 37, 1990.