— The Authors describe the favourable results obtained in 3 patients with Idiopathic Retroperitoneal Fibrosis (IRF) using a therapeutic protocol based on the association of prednisolone and cyclophosphamide. In 2 patients this therapy obtained a partial radiologic and total clinical remission; in the third case it guaranteed a stabilization of the results obtained by previous surgery. Given the absence of significant side effects, the protocol may be taken into consideration for practically all patients with TRF.
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