TRH.T is a tripeptide functioning as neurotransmitter which aids catecholamine, and especially norepinephrine, release. The neuromodulator action of TRH.T suggests that it could be helpful in the therapy of vesico-sphincteric dysfunctions. 26 patients with myelopathy were treated with TRH.T. The results show an improvement in both the neurological and urological picture. It would also seem possible that TRH.T could play an important role as a neurotransmitter and neuromodulator rather than a receptor-effector, especially in the lower urinary tract.
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