Abstract
19 patients suffering from symptomatic benign prostatic hyperplasia (BPH) underwent symptom score analysis, serum PSA level determination, trans-rectal ultrasound, flowmetry and pressure/flow (P/F) studies both before and at the end of a six month treatment period with finasteride, 5 mg a day. After six months of therapy, 89.5% of the pts had a significant symptomatic improvement, according to the decrease in symptom scores. Urodynamic evaluation showed a significant decrease in voiding pressure in 84% of the pts. 5 pts moved from the “obstructed” to the “unobstructed” section of the Abrams-Griffiths nomogram. 15/19 pts had a significant decrease in prostatic weight, as showed by means of ultrasound evaluation. This study confirms the efficacy of finasteride both in the symptomatic relief and in the functional improvement of BPH pts.
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