The fact that adenocarcinoma occurs in patients with ureterosigmoidostomy is well-documented in literature and the increased risk of carcinoma has been estimated to be 200 to 550 times that of the general population. No case of adenocarcinoma in ileal orthotopic or ileal continent reservoirs has been reported, due to the long latency period for carcinogenesis (20-25 years). We report 2 cases of bladder neoplasms of intestinal origin in patients who underwent, in 1956 and 1963, bladder augmentations for bladder tuberculosis. Our cases suggest that a long-term surveillance of continent urinary diversions is mandatory, as well as a close check on urinary cytology.
DaherN., GautierR., AbourachidH., DecaensC., BaraJ.: Rat colonic carcinogenesis after ureterosigmoidostomy: pathogenesis and immuno-histological study. J. Urol., 139: 1331–1335, 1988.
2.
EraklisA., FolkmanM.J.: Adenocarcinoma at the site of uretrosigmoidostomies for extrophy of the bladder. J. Pediatr. Surg., 13: 730–734, 1978.
UrdanetaL.F., DuddelC.D., CreevyC.D., BradleyJ.: Late development of primary carcinoma of the colon following ureterosigmoidostomy: report of three cases and literature review. Ann. Surg., 164: 503, 1966.
5.
GittesR.F.: Carcinogenesis in ureterosigmoidostomy. Urol. Clin. North Am., 13: 201–205, 1986.
6.
WarrenR.B., WarnerT.F.C.S. and HafezG. R.: Late development of colonic adenocarcinoma 49 years after ureterosigmoidostomy for extrophy of the bladder. J. Urol., 124: 550, 1980.
7.
EraklisA.J and FolkmanM. J.: Adenocarcinoma at the site of ureterosigmoidostomies for extrophy of the bladder. J. Ped. Surg., 13: 730, 1978.
8.
BartschH. and MontesanoR.: Relevance of nitrosamines to human cancer. Carcinogenesis, 5: 1381, 1984.
9.
CohenM.S., HilzM.E., DavisC.P and AndersonM. D.: Urinary carcinogen (nitrosamine) production in a rat animal model for ureterosigmoidostomy. J. Urol., 138: 449, 1987.
10.
CrisseyM.M., SteeleG.D and GittesR. F.: Rat model for carcinogenesis in ureterosigmoidostomy. Science, 07: 1079, 1980.
11.
PerzinK.H and BridgeM. F.: Adenomas of the small intestine a clinicopathologic review of 51 cases and a study of their relationship to carcinoma. Cancer, 48: 799, 1981.
12.
FilmerR.B., SpencerJ.R.: Malignancies in bladder augmentations and intestinal conduits. J. Urol., 143: 671–678, 1990.
13.
GazaigneJ., MozziconazziJ.G., ChebrouD.M., NtarudengaU.: Adenocarcinome colique après intervention de Coffey. J. d'Urol. (Paris), 99, 3: 146–149, 1993.
14.
GroschelJ., RiedaschG., KalbleT., TrickerA.R.: Nitrosamine excretion in patients with continental ileal reservoirs for urinary diversion. J. Urol., 148: 1013–1016, 1992.
