A case of primary renal sarcoma in a 72-year-old woman is described. Upon imaging techniques, including digitalized angiography, the tumour mass proved to be located in the upper left kidney. Despite gross infiltration of adjacent anatomic structures, radical excision of the tumour was possible. Histologically, the neoplasm was diffusely necrotic and composed of spindle and pleomorphic cells. This picture was considered consistent with the diagnosis of “high grade” fibrosarcoma. The immunohistochemical profile of the tumour cells confirmed this contention. The role of immunohistochemistry in the differential diagnosis of these malignancies is discussed.
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