Abstract
We submitted 229 tissue samples of 90 patients with prostatic hyperplasia and 51 patients with prostatic cancer to flow-cytometry DNA analysis. Samples were obtained with different modalities. Needle biopsy proves an effective method to provide adequate tissue samples. Results show that more than one sample is necessary in order to establish the cytometric pattern of hyperplastic and neoplastic prostate glands. Both aneuploidy and high S-phase can be found in BPH. Prostatic cancer is often heterogeneous at DNA analysis; aneuploidy can be found more frequently than in hyperplastic tissue and can be of different type.
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