Experimental Studies on the Removal of Paraffin from the Urinary Bladder with the Aid of Chemical Solvents

Abstract

The experimental studies in vitro and in vivo concerning the solubility of paraffin in the urinary bladder with the aid of chemical solvents such as: benzine, benzene, xylene, toluene, kerosene and turpentine were performed, It was found that a 3-gram lump of paraffin could be dissolved in 25 ml. of a solvent in 25 minutes. Kerosene and turpentine dissolved paraffin in 90 and 120 minutes, and so they were excluded from the experiments in vivo. On macro - and microscopic examination after 24 hours a severe suppurative cystitis with inflammatory peritoneal reaction could be found as a result of the application of solvent for 25 minutes. The use of the above method for clinical purposes in therefore inadvisable.