Bilateral renal cell carcinoma is rare and most commonly occurs in patients with background of hereditary and genetic diseases. Occurrence of bilateral renal cell carcinoma in native kidneys of a renal transplant patient is even more uncommon, and less than 10 cases have been reported in the English literature. Herein, we report our experience with the youngest renal transplant patient ever reported with bilateral renal cell carcinoma, who presented with intractable urinary tract infection. We also will review all of the reported cases of bilateral renal cell carcinoma in the last 20 years in the English literature according to the presentations, treatment modalities, prognosis, and graft outcome.
CloutierJAzizAInmanB, et al. Pediatric case report bilateral renal cell carcinoma in a child. Urology2012; 80: 430–433.
2.
TydenGWernerssonASandbergJ, et al. Development of renal cell carcinoma in living donor kidney grafts. Transplantation2000; 70(11): 1650–1656.
3.
ClaudonMPanescuVLe ChaffotecL, et al. Primary adenocarcinoma of the renal transplant. Nephrol Dial Transplant1998; 13(10): 2667–2670.
4.
PennI.De novo malignancies in paediatric organ transplant recipients. Pediatr Transplant1998; 2: 56–63.
5.
NoceALariaGDuranteO, et al. Bilateral native kidney neoplasia detected by ultrasound in functioning renal allograft recipient. Arch Ital Urol Androl2012; 84(4): 253–255.
6.
BingZTomaszewskiJE.Clear cell papillary renal cell carcinoma in the bilateral native kidneys after 2 years of renal transplantation: report of a case and review of the literature. Case Rep Transplant2011; 2011: 387645.
7.
NobushitaTHaraNNakagawaY, et al. Renal cell carcinomas arising from the allograft and bilateral native kidneys. Int J Urol2008; 15: 175–177.
8.
KlatteTSeitzCWaldertM, et al. Features and outcomes of renal cell carcinoma of native kidneys in renal transplant recipients. BJU Int2009; 105: 1260–1265.
