Restricted accessResearch articleFirst published online 1994-2
Employing L-Lactic Acid Powder in the Preparation of a Dry “Acid Concentrate” for use in a Bicarbonate-Based Dialysis Solution-Generating System: Experience in Hemodialysis Patients
By replacing the liquid acetic acid present in the “acid concentrate” of a bicarbonate-based dialysis solution-generating system with an equimolar amount of solid L-lactic acid and by using the dry forms of the remaining constituents, we were able to create a dry “acid concentrate” just prior to use, and successfully employed this “acid concentrate” to produce a bicarbonate-based solution to hemodialyze patients.
SargentJ.A., GotchF.A., LamM., ProwittM., KeenM.. Technical aspects of on-line proportioning of bicarbonate dialysate.Proc Clin Dial Transplant Forum1977; 7: 109–16.
2.
Technical bullettin on bicarbonate buffered hemodialysis. In: DymondD.D., EastmanD.F., eds. B-D Drake Willock, a division of BectonDickinson and Co., Portland, Oregon, USA, 1980.
3.
LedeboI.. Acetate vs bicarbonate in everyday dialysis.Gambro AB, Lund, Sweden, 1990.
4.
Van StoneJ.C.. Hemodialysis apparatus. In: DaugirdasJ.T., IngT.S., eds. Handbook of dialysis, 2nd ed.Boston: Little, Brown and Company, 1994; 30–52.
5.
BruceR.A., JonesJ.W., StraitG.B.. Anaerobic metabolic responses to acute maximal exercise in male athletes.Am Heart J1964; 67: 643–50.
6.
OrringerC.E., EustaceJ.C., WunschC.D., GardnerL.B.. Natural history of lactic acidosis after grand-mal seizures.N Engl J Med1977; 297: 796–9.
7.
DalaiS., YuA.W., GuptaD.K., KarP.M., IngT.S., DaugirdasJ.T.. L-lactate high-efficiency hemodialysis: hemodynamics, blood gas changes, potassium/phosphorus, and symptoms.Kidney Int1990; 38: 896–903.
8.
NolphK.D., TwardowskiZ.J., KhannaR.Tidal peritoneal dialysis with racemic or l-lactate solutions.Perit Dial Int1990; 10: 161–4.
9.
IngT.S., YuA.W., ThompsonK.D.Peritoneal dialysis using conventional, lactate-containing solution sterilized by ultrafiltration.Int J Artif Organs1992; 15: 658–60.
Instructions for preparing dialysis solution for use with Travenol Twin Coil Kidney™ and artificial kidney machine, Travenol Laboratories, Inc., Morton Grove, IL, USA, 1956.
12.
OhM.S., PhelpsK.R., TraubeM., Barbosa«SaldivarJ.L., BoxhillC., CarrollH.J.. D-lactic acid in a man with the short-bowel syndrome.N Engl J Med1979; 301: 249–52.
13.
NawabZ.M., ArmstrongM.K., WeissbergerL.E., IngT.S., HayashiJ.A., DaugirdasJ.T.. Use of lactate as a base in hemodialysis.Am J Nephrol1987; 7: 434–9.
14.
YamauchiM., KumagaiY., KamataT.Ezumi A, Shoji R. Clinical effects of sodium lactate dialysate on acetate intolerance.Nippon Jinzo Gakkai Shi1984; 26: 63–9.
