The frequency of myoglobinuric renal failure is estimated between 8 and 20%. Despite early onset of therapy often the use of renal substitution by hemodialysis or hemofiltration is required. This study of the clinical course of nine patients with myoglobinuric acute renal failure reveals continuous arterio-venous hemofiltration (CAVH) to have an effective clearance for myoglobin. Thus, the time until recovery of renal function as well as the frequency of secondary complications in rhabdomyolysis induced acute renal failure can be distinctly reduced.
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14.
AyerG., GrandchampA., WylerT., TrunigerB.Intrarenal hemodynamics in glycerol-induced myohemoglobinuric acute renal failure in the rat.Circulat Res1971; 24: 128–32.
15.
OkenD.E., DiBonaG.F., McDonaldF.D.Micropuncture studies of the recovery phase of myohemoglobinuric acute renal failure in the rat.J Clin Invest1970; 49: 730–5.
16.
RichterR.W., ChellenorY.B., PearsonJ., KagenL.J., HamiltonL.L., RamseyW.H.Acute myoglobinuria associated with heroin addiction.J Amer Med Ass1971; 17: 1172–6.
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AkmalM., GoldsteinD.A., TelkerN., WilkinsonE., MassryS.G.Resolution of muscle calcification in rhabdomyolysis and acute renal failure.Ann Intern Med1978; 89: 928–30.
18.
LlachF.A., FelsenfeldA.J., HausslerM.R.The pathophysiology of altered calcium metabolism in rhabdomyolysis-induced acute renal failure.New Engl J Med1981; 305: 117–21.
