A previously healthy, HIV-negative, 67-year-old man developed rapidly progressive glomerulonephritis. Following “pulse” methylprednisolone therapy he developed Pneumocystis carinii pneumonia. This complication should be recognized as a potential hazard of “pulse” steroid therapy.
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References
1.
HughesW.T.Pneumocystis Carinii pneumonia. New Engl J Med1977; 297: 1381–3.
2.
LockwoodC.M., PearsonT.A., ReesA.J., PetersD.K.Immunosuppression and plasma-exchange in the treatment of Goodpasture's Syndrome. Lancet, 1976; 1: 711–5.
3.
WingE.J., BrunsF.J., FraleyD.S., SegelD.P., AdlerS.Infectious complications with plasmapheresis in rapidly progressive glomerulonephritis. JAMA, 1980; 244: 2423–6.
4.
HindC.R.K., LockwoodC.M., PetersD.K.Plasmapheresis in rapidly progressive glomerulonephritis. Am J Med, 1978; 65: 564–7.
5.
Kincaid-SmithP., D'ApiceA.J.Plasmapheresis in rapidly progressive glomerulonephritis. Am J Med, 1978; 65: 564–7.
6.
KovacsJ.A., HeimerzJ.W., MacherA.M.Pneumocystis carinii pneumonia: A comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med, 1984; 100: 663–71.
7.
LockwoodC., PetersD.Plasma exchange in glomerulonephritis. Am Rev Med, 1980; 13: 167–79.
8.
O'NeilW.N., EtheridgeW.B., BloomerA.High-dose corticosteroids: Their use in treating idiopathic rapidly progressive glomerulonephritis. Arch Int Med, 1979; 139: 514–8.
9.
GrahamB.S., TuckerW.S.Opportunistic infections in endogenous Cushing's Syndrome. Ann Intern Med, 1984; 101: 334–8.
