Serum Phosphate Concentration with Relation to the Hematocrit Value in Uremic Patients on Chronic Hemodialysis

Abstract

The acute effects of hemodialysis on the serum inorganic phosphorus levels (sPi) with relation to the predialysis plasma volume (PV) and the hematocrit (Ht) values were studied in a group of chronic uremic patients on regular hemodialysis.

The results obtained confirmed the close direct correlation between predialysis sPi and fall in sPi induced by hemodialysis. Furthermore, the present fall in sPi induced by hemodialysis was found to be directly correlated to the PV values, and inversely to the HT values. An equation was derived from these data to predict in the individual patients the postdialysis sPi levels, utilizing both the predialysis sPi and the Ht values; this equation showed a better predictive capability than similar expression based on the use of the predialysis sPi value alone.

Keywords

Serum phosphate concentration Plasma volume Hematocrit Hemodialysis

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References

Gonella

: Relationship between plasma phosphate concentration and hematocrit in uremic patients undergoing hemodialysis. Nephron, 26, 100, 1980.

Lichtman

M.A.

, Miller

D.R.

, Freeman

R.B.

: Erythrocyte adenosine triphosphate depletion during hypophosphatemia in a uremic subject. New Engl. J. Med., 280, 240, 1969.

Muller-Wiefeld

D.E.

, Klare

, Scharer

: Effect of hemofiltration (HF) and hemodialysis (HD) on erythrocyte organic phosphate in uremic patients. Proc. EDTA, 16, 733, 1979.

Walker

G.S.

, Davison

A.M.

: Prediction of postdialysis hypophosphatemia. Br. Med. J., 2, 1060, 1977.

Gonella

, Fanara

, Maccheroni

, Mariani

: Serum creatinine (sCr) changes induced by hemodialysis (HD) with relation to the plasma volume/hematocrit (PV/HT). Inter. J. Artif. Organs, 5, 74, 1982.