Abstract
27 patients with chronic renal failure, 21 patients on chronic intermittend dialysis treatment and 27 healthy controls were tested for serum level of vitamin E estimated spectrophotometrically. Both patient groups had significant higher mean values (12.1 ± 1.2 and 7.2 ± 0.8 μg/ml respectively) in comparison with normal controls (4.6 ± 0.7 μg/ml). No correlation was found to serum creatinine, hematologic values, protein and lipoprotein concentration, nor to mode and duration of treatment regimes. Vitamin E was not extracted from blood throughout dialysis.
Under normal conditions of conservative or dialysis treatment of chronic renal failure patients vitamin E seems not to be a factor concerning uremic symptoms and there is no need for supplementation.
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