With hemoperfusion there is a sharp decline in the solute concentration of the blood compartment, but immediately after HP the concentration of these substances rises to the original level (post-Hp rebound). It may be inferred that the result would be better and the rebound phenomenon less marked if hemoperfusion could be combined with a continuous dialysis system such as CAPD.
The study was performed in 3 children of our CAPD programm. All patients were dialysed with 5 daily exchange each of one liter.
The patients underwent at 2-hours hemoperfusion with a charcoal column (Gambro Adsorba 150 c) once a week.
The data obtained with this form of treatment are indicative for a: significant increase of weekly clearance for uric acid and creatinine. low urea generation rate far 1–3 days after HP. low post-Hp rebound and reduced platelet count but not platelet activation.
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