Compliance of coil dialyzers follows a linear dependence on pressure when measured in saline; compliance measurements with non-wetting fluids are inappropriate and underestimate the blood compartment expansion experienced with pressure. The arithmetic mean of inlet and outlet pressures can be used to predict ultrafiltration rate independent of venous outlet pressure, and blood compartment volume varies both with inlet pressure and blood flow. The rejection of carbohydrate marker solutes increases from about 10% for 1,200 Daltons to 100% for 12,000 Dalton species.
ColtonC.K., HendersonL.W., FordC.A., LysaghtM.J.: Kinetics of hemodiafiltration.I. In vitro transport characteristics of a hollow fiber blood ultrafilter. J. Lab. Clin. Med., 85, 355, 1975.
2.
GagneuxE.A., LowrieE.G.: Mean transmembrane pressure within coil hemodialyzers.Dialysis and Transplantation.
3.
InouyeW.Y., EnglebergJ.: A simplified artificial dialyzer and ultrafilter.Surgical Forum, 4, 483, 1953.
4.
JaffrinM.Y., VantartG., GrangerA.: A concentration polarization model of hemofiltration with highly permeable membranes.ASAIO J., 73, 1979.
5.
KleinE., AutianJ., BowerJ.D.: Evaluation of hemodialyzers and dialysis membranes.U.S. Dept. Health, Education and Welfare. NIH, NIAMDD, Bethesda, Maryland (U.S.A.), DHEW Publication No. (NIH) 77–1294, p. 58, 1977.
6.
KleinE., HollandE.F., EberleK., WendtR.P.: Ultrafiltration rates and rejection of solutes by cellulosic hollow fibers. In: Synthetic Membranes: Hyperfiltration and Ultrafiltration Uses. ACS Symposium Series, No. 154, 1981.
7.
KleinE., SmithJ.K., HollandP.F., FlaggR.D.: Membrane and material evaluation. Permeabilities, physical and mechanical properties of hemodialysis membranes. Gulf South Research Institute Report No. AK-1-72-2221. Available from National Technical Information Service (PB 22506610 set A5) Springfield, VA (U.S.A.), 1973.
8.
KolffW.J., WalshingerB.: Further development of a coil kidney.J. Lab. Clin. Med., 47, 969, 1956.
9.
NolphK.D., VitaleF., HirszelP., HustedF.C., Van StoneJ.: Comparison of newer coil dialyzers.Nephron, 17, 81, 1976.
