An hemoperfusion (HP) column, packed with beads of a macroreticular MR ion exchange resin which were made biocompatible by coating with a fine layer of cross-linked human albumin, was applied to the removal of bilirubin (BIL) from a jaundiced 69-year old man with hepatic failure.
The column was found most suitable for BIL removal. However, the high volumetric mass transfer coefficient of the unconjugated (UC) BIL indicates that this column could best be used for BIL removal from babies suffering from unconjugated hyperbilirubinemia.
SidemanS., MorL., FishierL.S., ThalerI., BrandesJ.M.: Bilirubin removal by sorbent hemoperfusion from jaundiced blood. In: BrunnerG. (ed.) Proc. Int. Symp. Artificial Liver Support, Celle, Germany, June 1980. Springer Verlag, in press.
2.
GotchF.A., KeenM.L.: Precise control of minimal heparinization for high bleeding risk hemodialysis.Trans. Am. Soc. Artif. Intern. Organs, 23: 168–175, 1977.
