Concentration polarization phenomenon in new and re-used RP610 hemofilters during post-dilutional hemofiltration

Abstract

RP610 hemofilters have been used up to five times in Post-dilutional hemofiltration. Clearance studies were Performed «in vivo» (creatinine and phosphate) and «in vitro» (Cr⁵¹ EDTA, I¹³¹ Hypaque, Co⁵⁷ vitamin B₁₂, H³ Inulin, C¹⁴ Dextran, l¹²⁵ Albumin,) in new hemofilters and in those re-used once and five times. Hydraulic permeability and rejection coefficients, for the six markers different molecular weight, were also measured. Our preliminary results show that repeated cleansing with Amuchina^® does not alter the characteristics of RP610 hemofilters. A scintigraphic method is suggested for visualizing possible changes in polarized areas between new and re-used hemofilters.