Two surgical techniques have been developed in our laboratory to deal with identifiable problems in long-term artificial heart experiments. A right thoracotomy is used to deal with problems such as extensive bleeding, which occur in the immediate postoperative stage of the experiment, while a left thoracotomy is used in cases in Which the original implantation is preceded by more than one week, since extensive adhesions complicate the right thoracotomy at that stage. Pulmonary problems have been eliminated as a primary cause of difficulties after reoperation, but infection remains a serious problem.
FukumasuH., OlsenD.B., LawsonJ.H., IwayaF., MochizukiA., PonsA.B., and KesslerT.R.: Results of saving the natural outflow valves with the total artificial heart.Artif. Organs: Proc. Second Mtg. Int. Soc. Artif. Organs, (in press), 1979a.
2.
FukumasuH., IwayaF., OlsenD.B., LawsonJ.H., and KolffW.J.: Surgical implantation of the Jarvik-5 total artificial heart in a calf.Trans. Amer. Soc. Artif. Intern. Organs (in press), 1979b.
3.
FukumasuH., SmithL., JarvikR., LawsonJ., NielsenS., OlsenD., IwayaI., and KolffW.J.: Development of electric and hydroelectric hearts for future human application.Japan. J. Artif. Organs, (in press), 1979c.
4.
IwayaF., FukumasuH., OlsenD.B., NielsenS.D., LawsonJ.H., WhiteS., MochizukiT., and KolffW.J.: Studies of the remnant atria of the total artificial heart: P-wave response to the surgery, treadmill exercise and drugs.Artif. Organs: Proc. Second Mtg. Int. Soc. Artif. Organs, (in press), 1979a.
5.
IwayaF., FukumasuH., OlsenD.B., RazzecaK.J., McGillL.D., and KolffW.J.: Studies of atria with total artificial heart. 1. Histopathological findings of remnant atria and pannus formation.Japan. J. Artif. Organs (in press), 1979b.
6.
JarvikR.K., IsaacsonM.S., NielsenS.P., OrthJ., HiddemaP., and LandstraM.: Towards a portable human total artificial heart, utilizing a miniature electrohydraulic energy converter.Artif. Organs: Proc. Second Mtg. Int. Soc. Artif. Organs, (in press), 1979.
7.
KesslerT.R., PonsA.B., JarvikR.K., LawsonJ., RazzecaK., and KolffW.J.: Elimination of predilection sites for thrombus formation in the total artificial heart — before and after.Trans. Am. Soc. Artif. Intern. Organs24, 532, 1978.
8.
LawsonJ., OlsenD., KolffW.J., LiuW., HershgoldE.J., ColemanD., and Van KampenK.: A three-month survival of a calf with an artificial heart.J. Lab. Clin. Med., 87(5), 848–858, 1976.
9.
OlsenD.B., KolffJ., LawsonJ., StellwagF., CeccarelliV., FukumasuH., and KolffW.J.: Saving the aortic and pulmonary artery valves with total heart replacement.Trans. Am. Soc. Artif. Intern. Organs, 22, 476–486, 1976.
10.
OwenD.R., GalbraithJ., FukumasuH., KnightE.M., and KolffW.J.: Development of a new modular total artificial heart fabrication technique and its successful implementation.Abst. Amer. Soc. Artif. Intern. Organs, 7, 42, 1978.
11.
ThomaH., DeutschM., FaschingW., HaiderW., HorcherE., StellwagF., LosertU., MohlW., OsterH., SchedlR., UngerA.F., WeibkirchnerE., WolnerE., PolzerK., NavratilJ.: In-vivo testing of a closed loop driving unit for artificial hearts.Proc. Europ. Soc. Artif. Organs, 3, 27, 1976.
