The incidence of noncontact anterior cruciate ligament injuries in young to middle-aged athletes remains high. Despite early diagnosis and appropriate operative and nonoperative treatments, posttraumatic degenerative arthritis may develop. In a meeting in Atlanta, Georgia (January 2005), sponsored by the American Orthopaedic Society for Sports Medicine, a group of physicians, physical therapists, athletic trainers, biomechanists, epidemiologists, and other scientists interested in this area of research met to review current knowledge on risk factors associated with noncontact anterior cruciate ligament injuries, anterior cruciate ligament injury biomechanics, and existing anterior cruciate ligament prevention programs. This article reports on the presentations, discussions, and recommendations of this group.
Abubaker AO, Hebda PC, Gunsolley JN. Effects of sex hormones on protein and collagen content of the temporomandibular joint disc of the rat. J Oral Maxillofac Surg. 1996; 54: 721-727.
2.
Albright JP, Powell JW, Smith W, et al. Medial collateral ligament knee sprains in college football: effectiveness of preventive braces. Am J Sports Med. 1994; 22: 12-18.
3.
Allen MK, Glasoe WM. Metrecom measurement of navicular drop in subjects with anterior cruciate ligament injury. J Athl Train. 2000; 35: 403-406.
4.
Anderson AF, Dome DC, Gautam S, Awh MH, Rennirt GW. Correlation of anthropometric measurements, strength, anterior cruciate ligament size and intercondylar notch characteristics to sex differences in anterior cruciate ligament tear rates. Am J Sports Med. 2001; 29: 58-66.
5.
Anderson AF, Lipscomb AB, Liudahl KJ, Addlestone RB. Analysis of the intercondylar notch by computed tomography. Am J Sports Med. 1987; 15: 547-552.
6.
Arendt E, Dick R. Knee injury patterns among men and women in collegiate basketball and soccer: NCAA data and review of literature. Am J Sports Med. 1995; 23: 694-701.
7.
Arendt EA. Relationship between notch width index and risk of non-contact ACL injury. In: Griffin LY, ed. Prevention of Noncontact ACL Injuries. Rosemont, Ill: American Academy of Orthopaedic Surgeons; 2001:33-44.
8.
Arendt EA, Bershadsky B, Agel J. Periodicity of noncontact anterior cruciate ligament injuries during the menstrual cycle. J Gend Specif Med. 2002; 5: 19-26.
9.
Arnold JA, Coker TP, Heaton LM, Park JP, Harris WD. Natural history of anterior cruciate tears. Am J Sports Med. 1979; 7: 305-313.
10.
Aune AK, Cawley PW, Ekeland A. Quadriceps muscle contraction protects the anterior cruciate ligament during anterior tibial translation. Am J Sports Med. 1997; 25: 187-189.
11.
Bahr R, Krosshaug T. Understanding the injury mechanisms: a key component to prevent injuries in sport. Br J Sports Med. 2005; 39: 324-329.
12.
Baumhauer JF, Alosa DM, Renstrom AF, Trevino S, Beynnon B. A prospective study of ankle injury risk factors. Am J Sports Med. 1995; 23:564-570.
13.
Berns GS, Hull ML, Patterson HA. Strain in the anteromedial bundle of the anterior cruciate ligament under combination loading. J Orthop Res. 1992; 10: 167-176.
14.
Besier TF, Lloyd DG, Cochrane JL, Ackland TR. External loading of the knee joint during running and cutting maneuvers. Med Sci Sports Exerc. 2001; 33: 1168-1175.
15.
Beynnon BD, Bernstein I, Belisle A, et al. The effect of estradiol and progesterone on knee and ankle laxity. Am J Sports Med. 2005; 33: 1298-1304.
16.
Beynnon BD, Fleming BC, Churchill DL, Brown D. The effect of anterior cruciate ligament deficiency and functional bracing on translation of the tibia relative to the femur during nonweightbearing and weight-bearing. Am J Sports Med. 2003; 31: 99-105.
17.
Beynnon BD, Fleming BC, Labovitch R, Parsons B. Chronic anterior cruciate ligament deficiency is associated with increased anterior translation of the tibia during the transition from non-weightbearing to weightbearing. J Orthop Res. 2002; 20: 332-337.
18.
Beynnon BD, Howe JG, Pope MH, Johnson RJ, Fleming BC. The measurement of anterior cruciate ligament strain in vivo. J Biomech. 1992; 16: 1-12.
19.
Beynnon BD, Johnson RJ, Braun S, et al. The relationship between menstrual cycle phase and anterior cruciate ligament injury: a case-control study of recreational alpine skiers.. Am J Sports Med. In press. Epub January 25, 2006 doi:10.1177/0363546505282624
20.
Beynnon BD, Johnson RJ, Fleming BC, Stankewich CJ, Renstrom PA, Nichols CE. The strain behavior of the anterior cruciate ligament during squatting and active flexion-extension: a comparison of an open and a closed kinetic chain exercise. Am J Sports Med. 1997; 25: 823-829.
21.
Bonci CM. Assessment and evaluation of predisposing factors to anterior cruciate ligament injury. J Athl Train. 1999; 34: 155-164.
22.
Bronner S, Ojofeitimi S, Rose D. Injuries in a modern dance company: effect of comprehensive management on injury incidence and time loss. Am J Sports Med. 2003; 31: 365-373.
23.
Brown CN, Yu B, Kirkendall DT, et al. Effects of increased body mass index on lower extremity motion patterns in a stop-jump task: National Athletic Trainers Association annual meeting. Indianapolis, In, June 13-16, 2005. J Athl Train. 2005;404(suppl):5-5.
24.
Buchanan PA. Developmental Perspectives on Basketball Players' Strength, Knee Position in Landing, and ACL Injury Gender Differences[dissertation, research]. Bloomington, Ind: Indiana University; 2003.
25.
Caraffa A, Cerulli G, Projetti M, Aisa G, Rizzo A. Prevention of anterior cruciate ligament injuries in soccer: a prospective controlled study of proprioceptive training. Knee Surg Sports Traumatol Arthrosc. 1996; 4: 19-21.
26.
Centers for Disease Control and Prevention, National Center for Health Statistics. National Hospital Discharge Survey. Atlanta, Ga: Centers for Disease Control and Prevention; 1996.
27.
Cerulli G, Benoit DL, Lamontagne M, Caraffa A, Liti A. In vivo anterior cruciate ligament strain behaviour during a rapid deceleration movement: case report. Knee Surg Sports Traumatol Arthrosc. 2003; 11: 307-311.
28.
Chandrashekar N, Mansouri H, Slauterbeck J, Hashemi J. Sex-based differences in the tensile properties of the human anterior cruciate ligament. J Biomech. 2005 Dec 29; [Epub ahead of print] doi:10.1016/j.jbiomech.2005.10.031
29.
Chandrashekar N, Slauterbeck J, Hashemi J. Sex-based differences in the anthropometric characteristics of the anterior cruciate ligament and its relation to intercondylar notch geometry. Am J Sports Med. 2005; 33: 1492-1498.
30.
Chappell JD, Herman DC, Knight BS, Kirkendall DT, Garrett WE, Yu B. Effect of fatigue on knee kinetics and kinematics in stop-jump tasks. Am J Sports Med. 2005; 33: 1022-1029.
31.
Chappell JD, Yu B, Kirkendall DT, Garrett WE. A comparison of knee kinetics between male and female recreational athletes in stop-jump tasks. Am J Sports Med. 2002; 30: 261-267.
32.
Charlton WP, St John TA, Ciccotti MG, Harrison N, Schweitzer M. Differences in femoral notch anatomy between men and women: a magnetic resonance imaging study. Am J Sports Med. 2002; 30: 329-333.
33.
Chimera NJ, Swanik KA, Swanik CB, Straub SJ. Effects of plyometric training on muscle-activation strategies and performance in female athletes. J Athl Train. 2004; 39: 24-31.
34.
Colby S, Francisco A, Yu B, Kirkendall D, Finch M, Garrett W Jr. Electromyographic and kinematic analysis of cutting maneuvers: implications for anterior cruciate ligament injury. Am J Sports Med. 2000; 28: 234-240.
35.
Daniel DM, Stone ML, Dobson BE, Fithian DC, Rossman DJ, Kaufman KR. Fate of the ACL-injured patient: a prospective outcome study. Am J Sports Med. 1994; 22: 632-644.
36.
Decker MJ, Torry MR, Wyland DJ, Sterett WI, Richard Steadman J. Gender differences in lower extremity kinematics, kinetics, and energy absorption during landing. Clin Biomech (Bristol, Avon). 2003; 18: 662-669.
37.
Deie M, Sakamaki Y, Sumen Y, Urabe Y, Ikuta Y. Anterior knee laxity in young women varies with their menstrual cycle. Int Orthop. 2002; 26:154-156.
38.
DeMaio M. Biomechanical changes associated with participation in prevention programs. Paper presented at: Hunt Valley II Meeting; January 15, 2005; Atlanta, Ga.
39.
DeMorat G, Weinhold P, Blackburn T, Chudik S, Garrett W. Aggressive quadriceps loading can induce noncontact anterior cruciate ligament injury. Am J Sports Med. 2004; 32: 477-483.
40.
Dubey RK, Gillespie DG, Jackson EK, Keller PJ. 17beta-estradiol, its metabolites, and progesterone inhibit cardiac fibroblast growth. Hypertension. 1998; 31: 522-528.
41.
Dürselen L, Claes L, Kiefer H. The influence of muscle forces and external loads on cruciate ligament strain. Am J Sports Med. 1995; 23: 129-136.
42.
Ettlinger CF, Johnson RJ, Shealy JE. A method to help reduce the risk of serious knee sprains incurred in alpine skiing. Am J Sports Med. 1995; 23: 531-537.
43.
Feagin JA Jr, Lambert KL, Cunningham RR, et al. Consideration of the anterior cruciate ligament in skiing. Clin Orthop Relat Res. 1987; 216: 13-18.
44.
Ferretti A, Conteduca F, DeCarli A, Fontana M, Mariani PP. Osteoarthritis of the knee after ACL reconstruction. Int Orthop. 1991; 15:367-371.
45.
Fischer GM. Comparison of collagen dynamics in different tissues under the influence of estradiol. Endocrinology. 1973; 93: 1216-1218.
46.
Fithian DC, Paxton EW, Stone ML, et al. Prospective trial of a treatment algorithm for the management of the anterior cruciate ligament injured knee. Am J Sports Med. 2005; 33: 335-346.
47.
Fleming BC, Beynnon BD, Renstrom PA, Johnson RJ, Peura GD, Nichols CE. In vivo measurement of ACL strain: applications to rehabilitation. Sportorthopaadie Sporttraumatologie. 1992; 16: 133-142.
48.
Fleming BC, Renstrom PA, Ohlen G, et al. The gastrocnemius muscle is an antagonist of the anterior cruciate ligament. J Orthop Res. 2001; 19:1178-1184.
49.
Flynn RK, Pedersen CL, Birmingham TB, Kirkley A, Jackowski D, Fowler PJ. The familial predisposition toward tearing the anterior cruciate ligament: a case control study.Am J Sports Med. 2005;33:23-28.
50.
Ford KR, Myer GD, Hewett TE. Valgus knee motion during landing in high school female and male basketball players. Med Sci Sports Exerc. 2003; 35: 1745-1750.
51.
Ford KR, Myer GD, Toms HE, Hewett TE. Gender differences in the kinematics of unanticipated cutting in young athletes. Med Sci Sports Exerc. 2005; 37: 124-129.
52.
Garrett WE Jr. Anterior cruciate ligament injury: pathophynology and current therapeutic principles. Paper presented at: 71st Annual Meeting of the American Academy of Orthopaedic Surgeons; March 10-14, 2004; San Francisco, Calif.
53.
Garrett WE Jr. Congruence between existing prevention programs and research on risk factors and mechanisms of noncontact ACL injury. Paper presented at: Hunt Valley II Meeting; January 15, 2005; Atlanta, Ga.
54.
Garrick JG, Requa RK. Anterior cruciate ligament injuries in men and women: how common are they? In: Griffin LY, ed. Prevention of Non-contact ACL Injuries. Rosemont, Ill: American Academy of Orthopaedic Surgeons; 2001:1-10.
55.
Gilchrist JR, Mandelbaum BR, Melancon H. A randomized controlled trial to prevent anterior cruciate ligament injuries in female collegiate soccer players [abstract 6-7]. Paper presented at: American Orthopaedic Society for Sports Medicine Specialty Day; March 13, 2004; San Francisco, Calif.
56.
Gottlob CA, Baker CL, Pellissier JM, Colvin L. Cost effectiveness of anterior cruciate ligament reconstruction in young athletes. Clin Orthop Relat Res. 1999; 367: 272-282.
57.
Granata KP, Padua DA, Wilson SE. Gender differences in active musculoskeletal stiffness, part II: quantification of leg stiffness during functional hopping tasks. J Electromyogr Kinesiol. 2002; 12: 127-135.
58.
Granata KP, Wilson SE, Padua DA. Gender differences in active musculoskeletal stiffness, part I: quantification in controlled measurements of knee joint dynamics. J Electromyogr Kinesiol. 2002; 12: 119-126.
59.
Graves JE, Pollock ML, Leggett SH, Braith RW, Carpenter DM, Bishop LE. Effect of reduced training frequency on muscular strength. Int J Sports Med. 1988; 9: 316-319.
60.
Gray J, Taunton JE, McKenzie DC, Clement DB, McConkey JP, Davison RG. A survey of injuries to the anterior cruciate ligament of the knee in female basketball players. Int J Sports Med. 1985; 6: 314-316.
61.
Griffin LY, ed. Prevention of Noncontact ACL Injuries. Rosemont, Ill: American Academy of Orthopaedic Surgeons; 2001.
62.
Griffin LY, Agel J, Albohm MJ, et al. Noncontact anterior cruciate ligament injuries: risk factors and prevention strategies. J Am Acad Orthop Surg. 2000; 8: 141-150.
63.
Griffis ND, Nequist SW, Yearout K, et al. Injury prevention of the anterior cruciate ligament. Abstracted in the American Orthopaedic Society for Sports Medicine: Meeting Abstracts, Symposia, and Instructional Courses, 15th Annual Meeting; June 19-22, 1989; Traverse City, Mich.
64.
Hama H, Yamamuro T, Takeda T. Experimental studies on connective tissue of the capsular ligament: influences of aging and sex hormones. Acta Orthop Scand. 1976; 47: 473-479.
65.
Hame SL, Oakes DA, Markolf KL. Injury to the anterior cruciate ligament during alpine skiing: a biomechanical analysis of tibial torque and knee flexion angle. Am J Sports Med. 2002; 30: 537-540.
66.
Harner CD, Paulos LE, Greenwald AE, Rosenberg TD, Cooley VC. Detailed analysis of patients with bilateral anterior cruciate ligament injuries. Am J Sports Med. 1994; 22: 37-43.
67.
Heiderscheit BC, Hamill J, Caldwell GE. Influence of Q-angle on lower-extremity running kinematics. J Orthop Sports Phys Ther. 2000; 30:271-278.
68.
Heidt RS, Sweeterman LM, Carlonas RL, Traub JA, Tekulve FX. Avoidance of soccer injuries with preseason conditioning. Am J Sports Med. 2000; 28: 659-662.
69.
Heitz NA. Hormonal changes throughout the menstrual cycle and increased anterior cruciate ligament laxity in females. J Athl Train. 1999; 343: 144-149.
70.
Hewett TE, Lindenfeld TN, Riccobene JV, Noyes FR. The effect of neuromuscular training on the incidence of knee injury in female athletes: a prospective study. Am J Sports Med. 1999; 27: 699-706.
71.
Hewett TE, Ford KR, Myer GD. Anterior cruciate ligament injuries in female athletes: Part 2, A meta-analysis of neuromuscular interventions aimed at injury prevention. Am J Sports Med. 2006;34(3):490-498.
72.
Hewett TE, Myer GD, Ford KR. Decrease in neuromuscular control about the knee with maturation in female athletes. J Bone Joint Surg Am. 2004; 86: 1601-1608.
73.
Hewett TE, Myer GD, Ford KR, et al. Biomechanical measures of neuromuscular control and valgus loading of the knee predict anterior cruciate ligament injury risk in female athletes: a prospective study. Am J Sports Med. 2005; 33: 492-501.
74.
Hewett TE, Stroupe AL, Nance TA, Noyes FR. Plyometric training in female athletes: decreased impact forces and increased hamstring torques. Am J Sports Med. 1996; 24: 765-773.
75.
Holm I, Fosdahl MA, Friis A, Risberg MA, Myklebust G, Steen H. Effect of neuromuscular training on proprioception, balance, muscle strength, and lower limb function in female team handball players. Clin J Sport Med. 2004; 14: 88-94.
76.
Horton MG, Hall TL. Quadriceps femoris muscle angle: normal values and relationships with gender and selected skeletal measures. Phys Ther. 1989; 69: 897-901.
77.
Huston LJ, Vibert B, Ashton-Miller JA, Wojtys EM. Gender differences in knee angle when landing from a drop-jump. Am J Knee Surg. 2001; 14:215-219.
78.
Huston LJ, Wojtys EM. Neuromuscular performance characteristics in elite female athletes. Am J Sports Med. 1996; 24: 427-436.
79.
Hvid I, Andersen LI, Schmidt H. Chondromalacia patellae: the relation to abnormal patellofemoral joint mechanics. Acta Orthop Scand. 1981; 52:661-666.
80.
Irmischer BS, Harris C, Pfeiffer RP, DeBeliso MA, Adams KJ, Shea KG. Effects of a knee ligament injury prevention exercise program on impact forces in women. J Strength Cond Res. 2004; 18: 703-707.
81.
Karageanes SJ, Blackburn K, Vangelos ZA. The association of the menstrual cycle with the laxity of the anterior cruciate ligament in adolescent female athletes. Clin J Sport Med. 2000; 10: 162-168.
82.
Kibler WB, Livingston B. Closed-chain rehabilitation for upper and lower extremities. J Am Acad Orthop Surg. 2001; 9: 412-421.
83.
Knapik JJ, Bauman CL, Jones BH, Harris JM, Vaughan L. Preseason strength and flexibility imbalances associated with athletic injuries in female collegiate athletes. Am J Sports Med. 1991; 19: 76-81.
84.
Knapik JJ, Sharp MA, Canham-Chervak M, Hauret K, Patton JF, Jones BH. Risk factors for training-related injuries among men and women in basic combat training. Med Sci Sports Exerc. 2001; 33: 946-954.
85.
Kocher MS, Sterett WI, Briggs KK, Zurakowski D, Steadman JR. Effect of functional bracing on subsequent knee injury in ACL-deficient professional skiers. J Knee Surg. 2003; 16: 87-92.
86.
Lambson RB, Barnhill BS, Higgins RW. Football cleat design and its effect on anterior cruciate ligament injuries: a 3-year prospective study. Am J Sports Med. 1996; 24: 155-159.
87.
Lamontagne M, Benoit DL, Ramsey DK, Caraffa A, Cerulli G. What can we learn from in vivo biomechanical investigations of lower extremity. Proceedings of XXIII International Symposium on Biomechanics in Sports; August 22-27, 2005; Beijing, China.
88.
Landgren BM, Unden AL, Diczfalusy E. Hormonal profile of the cycle in 68 normally menstruating women. Acta Endocrinol. 1980; 94: 89-98.
89.
LaPrade RF, Burnett QM II. Femoral intercondylar notch stenosis and correlation to anterior cruciate ligament injuries: a prospective study. Am J Sports Med. 1994; 22: 198-203.
90.
Lephart SM, Ferris CM, Riemann BL, Myers JB, Fu FH. Gender differences in strength and lower extremity kinematics during landing. Clin Orthop Relat Res. 2002; 401: 162-169.
91.
Liu SH, al-Shaikh R, Panossian V, et al. Primary immunolocalization of estrogen progesterone target cells in the human anterior cruciate ligament. J Orthop Res. 1996; 14: 526-533.
92.
Livingston LA. The quadriceps angle: a review of the literature. J Orthop Sports Phys Ther. 1998; 28: 105-109.
93.
Lohmander LS, Ostenberg A, Englund M, Roos H. High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury. Arthritis Rheum. 2004; 50: 3145-3152.
94.
Loudon JK, Jenkins W, Loudon KL. The relationship between static posture and ACL injury in female athletes. J Orthop Sports Phys Ther. 1996; 24: 91-97.
95.
Lund-Hanssen H, Gannon J, Engebretsen L, Holen KJ, Anda S, Vatten L. Intercondylar notch width and risk of anterior cruciate ligament rupture: a case-control study in 46 female handball players. Acta Orthop Scand. 1994; 65: 529-532.
Malinzak RA, Colby SM, Kirkendall DT, Yu B, Garrett WE. A comparison of knee joint motion patterns between men and women in selected athletic tasks. Clin Biomech (Bristol, Avon). 2001; 16: 438-445.
98.
Mandelbaum BR, Silvers HJ, Watanabe DS, et al. Effectiveness of a neuromuscular and proprioceptive training program in preventing anterior cruciate ligament injuries in female athletes: 2-year follow up. Am J Sports Med. 2005; 33: 1003-1010.
99.
Markolf KL, Burchfield DM, Shapiro MM, Shepard MF, Finerman GA, Slauterbeck JL. Combined knee-loading states that generate high anterior cruciate ligament forces. J Orthop Res. 1995; 13: 930-935.
100.
McDevitt ER, Taylor DC, Miller MD, et al. Functional bracing after anterior cruciate ligament reconstruction: a prospective, randomized, multicenter study. Am J Sports Med. 2004; 32: 1887-1892.
101.
McIntosh AS. Risk compensation, motivation, injuries, and biomechanics in competitive sport. Br J Sports Med. 2005; 39: 2-3.
102.
McLean SG, Huang X, Su A, Van Den Bogert AJ. Sagittal plane biomechanics cannot injure the ACL during sidestep cutting. Clin Biomech (Bristol, Avon). 2004; 19: 828-838.
103.
McLean SG, Walker K, Ford KR, Myer GD, Hewett TE, van den Bogert AJ. Evaluation of a two dimensional analysis method as a screening and evaluation tool for anterior cruciate ligament injury. Br J Sports Med. 2005; 39: 355-362.
104.
McNair PJ, Marshall RN, Matheson JA. Important features associated with acute anterior cruciate ligament injury. N Z Med J. 1990; 103:537-539.
105.
McNitt-Gray JL. Kinetics of the lower extremity during drop landings from three heights. J Biomech. 1993; 26: 1037-1046.
106.
Meeuwisse WH. Assessing causation in sport injury: a multifactorial model. Clin J Sport Med. 1994; 4: 166-170.
107.
Meyers MC, Barnhill BS. Incidence, causes, and severity of high school football injuries on FieldTurf versus natural grass: a 5-year prospective study. Am J Sports Med. 2004; 32: 1626-1638.
108.
Milburn PD, Barry EB. Shoe-surface interaction and the reduction of injury in rugby union. Sports Med. 1998; 25: 319-327.
109.
Miura K, Ishibashi Y, Tsuda E, Okamura Y, Otsuka H, Toh S. The effect of local and general fatigue on knee proprioception. Arthroscopy. 2004; 20: 414-418.
110.
Mizuno Y, Kumagai M, Mattessich SM, et al. Q-angle influences tibiofemoral and patellofemoral kinematics. J Orthop Res. 2001; 19: 834-840.
111.
More RC, Karras BT, Neiman R, Fritschy D, Woo SL, Daniel DM. Hamstrings: an anterior cruciate ligament protagonist. An in vitro study. Am J Sports Med. 1993; 21: 231-237.
112.
Moul JL. Differences in selected predictors of anterior cruciate ligament tears between male and female NCAA Division I collegiate basketball players. J Athl Train. 1998; 33: 118-121.
113.
Mujika I, Padilla S. Cardiorespiratory and metabolic characteristics of detraining in humans. Med Sci Sports Exerc. 2001; 33: 413-421.
114.
Muneta T, Takakuda K, Yamamoto H. Intercondylar notch width and its relation to the configuration and cross-sectional area of the anterior cruciate ligament: a cadaveric knee study. Am J Sports Med. 1997; 25: 69-72.
115.
Murphy DF, Connolly DA, Beynnon BD. Risk factors for lower extremity injury: a review of the literature. Br J Sports Med. 2003; 37: 13-29.
116.
Myer GD, Ford KR, Palumbo JP, Hewett TE. Neuromuscular training improves performance and lower extremity biomechanics in female athletes. J Strength Cond Res. 2005; 19: 51-60.
117.
Myklebust G, Bahr R. Return to play guidelines after anterior cruciate ligament surgery. Br J Sports Med. 2005; 39: 127-131.
118.
Myklebust G, Engebretsen L, Braekken IH, Skjolberg A, Olsen OE, Bahr R. Prevention of anterior cruciate ligament injuries in female team handball players: a prospective intervention study over three seasons. Clin J Sport Med. 2003; 13: 71-78.
119.
Myklebust G, Maehlum S, Engebretsen L, Strand T, Solheim E. Registration of cruciate ligament injuries in Norwegian top level team handball: a prospective study covering two seasons. Scand J Med Sci Sports. 1997; 7: 289-292.
120.
Myklebust G, Maehlum S, Holm I, Bahr R. A prospective cohort study of anterior cruciate ligament injuries in elite Norwegian team handball. Scand J Med Sci Sports. 1998; 8: 149-153.
121.
Najibi S, Albright JP. The use of knee braces, part 1: prophylactic knee braces in contact sports. Am J Sports Med. 2005; 33: 602-611.
122.
Nichols A, Yu L, Garrick J, et al. Anterior cruciate ligament injury in two international figure skaters: mechanism of injury. Paper presented at: Third Congress on the Sports Medicine and Sports Science of Skating; January 1998; Philadelphia, Pa.
123.
Noyes FR, Dunworth LA, Andriacchi TP, Andrews M, Hewett TE. Knee hyperextension gait abnormalities in unstable knees: recognition and preoperative gait retraining. Am J Sports Med. 1996; 24: 35-45.
124.
Olsen L, Scanlan A, Mackay M, et al. Strategies for prevention of soccer related injuries: a systematic review. Br J Sports Med. 2004; 38:89-94.
125.
Olsen OE, Myklebust G, Engretsen L, Bahr R. Injury mechanisms for anterior cruciate ligament injuries in team handball: a systematic video analysis. Am J Sports Med. 2004; 32: 1002-1012.
126.
Olsen OE, Myklebust G, Engebretsen L, Holme I, Bahr R. Exercises to prevent lower limb injuries in youth sports: cluster randomized controlled trial. BMJ. 2005;330:449-449.
127.
Olsen OE, Myklebust G, Engebretsen L, Holme I, Bahr R. Relationship between floor type and risk of ACL injury in team handball. Scand J Med Sci Sports. 2003; 13: 299-304.
128.
Orchard J. Is there a relationship between ground and climatic conditions and injuries in football?Sports Med. 2002;32:419-432.
129.
Orchard J, Seward H, McGivern J, Hood S. Rainfall, evaporation and the risk of non-contact anterior cruciate ligament injury in the Australian Football League. Med J Aust. 1999; 170: 304-306.
130.
Ostenberg A, Roos H. Injury risk factors in female European football: a prospective study of 123 players during one season. Scand J Med Sci Sports. 2000; 10: 279-285.
131.
Padua DA, Carcia CR, Arnold BL, Granata KP. Gender differences in leg stiffness and stiffness recruitment strategy during two-legged hopping. J Mot Behav. 2005; 37: 111-125.
132.
Paterno MV, Myer GD, Ford KR, Hewett TE. Neuromuscular training improves single-limb stability in young female athletes. J Orthop Sports Phys Ther. 2004; 34: 305-316.
133.
Pfeiffer RP, Shea KG, Grandstrand S, et al. Effects of a knee ligament injury prevention (KLIP) program on the incidence of noncontact ACL injury: a two-year prospective study of exercise intervention in high school female athletes. Podium presentation at: American Orthopaedic Society for Sports Medicine Specialty Day; March 13, 2004; San Francisco, Calif.
134.
Pollard CD, Davis IM, Hamill J. Influence of gender on hip and knee mechanics during a randomly cued cutting maneuver. Clin Biomech (Bristol, Avon). 2004; 19: 1022-1031.
Roos H, Adalberth T, Dahlberg L, Lohmander LS. Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: the influence of time and age. Osteoarthritis Cartilage. 1995; 3: 261-267.
137.
Roos HP, Ornell M, Gardsell P, Lohmander LS, Lindstrand A. Soccer after anterior cruciate ligament injury: an incompatible combination? A national survey of incidence and risk factors and 7 year follow-up of 310 players. Acta Orthop Scand. 1995; 66: 107-112.
138.
Schickendantz MS, Weiker GG. The predictive value of radiographs in the evaluation of unilateral and bilateral anterior cruciate ligament injuries. Am J Sports Med. 1993; 21: 110-113.
139.
Seneviratne A, Attia E, Williams RJ, Rodeo SA, Hannafin JA. The effect of estrogen on ovine anterior cruciate ligament fibroblasts: cell proliferation and collagen synthesis. Am J Sports Med. 2004; 32: 1613-1618.
140.
Shambaugh JP, Klein A, Herbert JH. Structural measures as predictors of injury in basketball players. Med Sci Sports Exerc. 1991; 23: 522-527.
141.
Shelbourne KD, Davis TJ, Klootwyk TE. The relationship between intercondylar notch width of the femur and the incidence of anterior cruciate ligament tears: a prospective study. Am J Sports Med. 1998; 26: 402-408.
142.
Shelbourne KD, Kerr B. The relationship of femoral intercondylar notch width to height, and sex in patients with intact anterior cruciate ligaments. Am J Knee Surg. 2001; 14: 92-96.
143.
Shikata J, Sanada H, Tamamuro T, Takeda T. Experimental studies of the elastic fiber of the capsular ligament: influence of aging and sex hormones on the hip joint capsule of rats. Connect Tissue Res. 1979; 7: 21-27.
144.
Shultz SJ, Gansneder BG, Sander TC, Kirk SE, Perrin DH. Absolute hormone levels predict the magnitude of change in knee laxity across the menstrual cycle. J Orthop Res.In press.
145.
Shultz SJ, Kirk SE, Johnson ML, Sander TC, Perrin DH. Relationship between sex hormones and anterior knee laxity across the menstrual cycle. Med Sci Sports Exerc. 2004;36:1165-1174.
146.
Shultz SJ, Sander TC, Kirk SE, Perrin DH. Sex differences in knee joint laxity change across the female menstrual cycle. J Sports Med Phys Fitness. 2005;45(4):594-603.
147.
Silvers H. Components of prevention programs presentation. Paper presented at: Hunt Valley II Meeting; January 15, 2005; Atlanta, Ga.
148.
Sitler M, Ryan J, Hopkinson W, et al. The efficacy of a prophylactic knee brace to reduce knee injuries in football: a prospective randomized study at West Point. Am J Sports Med. 1990; 18: 310-315.
149.
Slauterbeck JR, Clevenger C, Lundberg W, Burchfield DM. Estrogen level alters the failure load of the rabbit anterior cruciate ligament. J Orthop Res. 1999; 17: 405-408.
150.
Slauterbeck JR, Fuzie SF, Smith MP, et al. The menstrual cycle, sex hormones, and anterior cruciate ligament injury. J Athl Train. 2002; 37:275-280.
151.
Smith J, Szczerba JE, Arnold BL, Martin DE, Perrin DH. Role of hyperpronation as a possible risk factor for anterior cruciate ligament injuries. J Athl Train. 1997; 32: 25-28.
152.
Soderman K, Werner S, Pietila T, Engstrom B, Alfredson H. Balance board training: prevention of traumatic injuries of the lower extremities in female soccer players? A prospective randomized intervention study. Knee Surg Sports Traumatol Arthrosc. 2000; 8: 356-363.
153.
Sommerlath K, Lysholm J, Gillquist J. The long-term course after treatment of acute anterior cruciate ligament ruptures: a 9 to 16 year follow-up. Am J Sports Med. 1991; 19: 156-162.
154.
Souryal TO, Freeman TR. Intercondylar notch size and anterior cruciate ligament injuries in athletes: a prospective study. Am J Sports Med. 1993; 21: 535-539.
155.
Strickland SM, Belknap TW, Turner SA, Wright TM, Hannafin JA. Lack of hormonal influences on mechanical properties of sheep knee ligaments. Am J Sports Med. 2003; 31: 210-215.
156.
Teitz CC. Video analysis of ACL injuries. In: Griffin LY, ed. Prevention of Noncontact ACL Injuries. Rosemont, Ill: American Academy of Orthopaedic Surgeons; 2001:87-92.
157.
Teitz CC, Lind BK, Sacks BM. Symmetry of the femoral notch width index. Am J Sports Med. 1997; 25: 687-690.
158.
Torzilli PA, Deng X, Warren RF. The effect of joint-compressive load and quadriceps muscle force on knee motion in the intact and anterior cruciate ligament–sectioned knee. Am J Sports Med. 1994; 22: 105-112.
159.
Uhorchak JM, Scoville CR, Williams GN, Arciero RA, St Pierre P, Taylor DC. Risk factors associated with noncontact injury of the anterior cruciate ligament: a prospective four-year evaluation of 859 West Point cadets. Am J Sports Med. 2003; 31: 831-842.
160.
Van Lunen BL, Roberts J, Branch JD, Dowling EA. Association of menstrual-cycle hormone changes with ACL laxity measurements. J Athl Train. 2003; 38: 298-303.
161.
Von Porat A, Roos EM, Roos H. High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes. Ann Rheum Dis. 2004; 63: 269-273.
162.
Wascher DC, Markolf KL, Shapiro MS, Finerman GA. Direct in vitro measurement of forces in the cruciate ligaments, part I: the effect of multiplane loading in the intact knee. J Bone Joint Surg Am. 1993; 75:377-386.
163.
Washington EL. Musculoskeletal injuries in theatrical dancers: site, frequency, and severity. Am J Sports Med. 1978; 6: 75-98.
164.
Wedderkopp N, Kaltoft M, Holm R, Froberg K. Comparison of two intervention programmes in young female players in European handball: with and without ankle discs. Scand J Med Sci Sports. 2003; 13: 371-375.
165.
White KK, Lee SS, Cutuk A, Hargens AR, Pedowitz RA. EMG power spectra of intercollegiate athletes and anterior cruciate ligament injury risk in females. Med Sci Sports Exerc. 2003; 35: 371-376.
166.
Wojtys EM, Ashton-Miller JA, Huston LJ. A gender-related difference in the contribution of the knee musculature to sagittal-plane shear stiffness in subjects with similar knee laxity. J Bone Joint Surg Am. 2002; 84: 10-16.
167.
Wojtys EM, Huston LJ, Boynton MD, Spindler KP, Lindenfeld TN. The effect of the menstrual cycle on anterior cruciate ligament injuries in women as determined by hormone levels. Am J Sports Med. 2002; 30: 182-188.
168.
Wojtys EM, Huston LJ, Schock HJ, Boylan JP, Ashton-Miller JA. Gender differences in muscular protection of the knee in torsion in size-matched athletes. J Bone Joint Surg Am. 2003; 85: 782-789.
169.
Wojtys EM, Wylie BB, Huston LJ. The effects of muscle fatigue on neuromuscular function and anterior tibial translation in healthy knees. Am J Sports Med. 1996; 24: 615-621.
170.
Woodford-Rogers B, Cyphert L, Denegar CR. Risk factors for anterior cruciate ligament injury in high school and college athletes. J Athl Train. 1994; 29: 343-346.
171.
Yu B, Herman D, Preston J, Lu W, Kirkendall DT, Garrett WE. Immediate effects of a knee brace with a constraint to knee extension on knee kinematics and ground reaction forces in a stop-jump task. Am J Sports Med. 2004; 32: 1136-1143.
172.
Yu B, McClure SB, Onate JA, Guskiewicz KM, Kirkendall DT, Garrett WE. Age and gender effects on lower extremity kinematics of youth soccer players in a stop-jump task. Am J Sports Med. 2005; 33: 1356-1364.
173.
Yu WD, Liu S, Hatch JD, Panossian V, Finerman GA. Effect of estrogen on cellular metabolism of the human anterior cruciate ligament. Clin Orthop Relat Res. 1999; 366: 229-238.
174.
Yu WD, Panossian V, Hatch JD, Liu SH, Finerman GA. Combined effects of estrogen and progesterone on the anterior cruciate ligament. Clin Orthop Relat Res. 2001; 383: 268-281.
