APPROACH FOR PERIODONTAL DISEASE BY BI-DIGITAL O-RING TEST (THE SECOND REPORT) EXAMINATION OF EFFECT OF THE TOOTHPASTE MIXED WITH INDIGO PLANT EXTRACT

1) Hashimoto Takaharu Aga Hajime Chaen Hiroto Fukuda Shigeharu Kurimoto Masashi :Isolation and Identification of Anti-Hricobacter pylori Compounds from Polygonum tinctorium Lour. Natural Medicines 53( 1 ):27-31,1999

2) Kataoka Mari Hirata Kyoko Kunikata Toshio Ushio Shimpei Iwaki Kanso Ohashi Kunihiro Ikeda Masao Kurimoto Masashi :Antibacterial action of tryptanthrin and kaempferol, isolated from the indigo plant(Polygonum tinctorium Lour.),against Hericobacter pylori-in- fected Mongolian gerbils. J Gastroenterol36:5-9,2001

3) Tatefuji Tomoki Aga Miho Kunikata Toshio Ikeda Masao Kurimoto Masashi : Antiviral Effect of Polygonum tinctorium Lour. Extracts on Virus-Infected Cells. Natural Medicines 53(6):297-301,1999

4) Ishihara Tatsuya Okura Takanori Kohno Keizo Tanimoto Tadao Ikegami Hakuo Kurimoto Masasi : Polygonum tinctorium extract suppresses nitric oxide production by activated macrophages through inhibiting inducible nitric oxide synthase expression. Journal of Ethnopharmacology 72:141-150,2000

5) Ishihara Tatsuya Kohno Keizo Ushio Shimpei Iwaki Kanso Ikeda Masao Kurimoto Masashi : Tryptanthrin inhibits nitric oxide and prostaglandin E2 synthesis by murine macrophages. European Journal of Pharmacology 470:197-204,2000

6) Kimoto T Yamamoto Y Hino K Koya S Aga H Hashimoto T Hanaya T Arai S Ikeda M Fukuda S Kurimoto M : Cytotoxic effects of substances in indigo plant (Polygonum tinctorium Lour.) on malignant tumor cells (in Japanese).Natural Medicine 53(2):72-79,1999

7) Kimoto T Koya S Hino K Yamamoto Y Aga H Hashimoto T Masaki N Mukai N Hanaya T Arai S Ikeda M Fukuda S Kurimoto M : Protection by indigo plant (Polygonum tinctorium Lour.) against renal oxidative damage in mice treated with ferric nitrilotriacetate (in Japanese). Natural Medicine 53(6):291-296,1999

8) Inoue S Takayama S Ushio S Iwaki K Ohashi K Masaki N Fukuda S Ikeda M Kurimoto M :Improvement of high fat diet-induced hyperlipidemia by Polygonum tinctorium Lour, (in Japanese). Natural Medicines, 54(5):261-264,2000.

9) Iwaki Kanso Kurimoto Masashi : Ai-Ishokudougen-(in Japanese) Nihon Bunkyou Shuppan Co.,Okaya, 2001

10) Sunayama T Masaki N Fukuda S : Anti-inflammation of Polygonum tinctorium Lour, extract— clinical trials for candidiasis (in Japanese). Med Biol 139:29-32,1999

11) Iwaki Kanso Koya-Miyata Satomi Kohno Keizo Ushio Shimpei Fukuda Shigeharu : Antimicrobial activity of Polygonum tinctorium Lour extract against oral pathogenic bacteria. Journal of Natural Medicines, 60,121-125,2006

12) Sunagawa M Fukuoka H Koyama Y Fukuoka A : Approach for Periodontal Disease by Bi-Digital O-Ring Test~Examination of Effect of Indigo Paste~.6th International Symposium on the Bi-Digital O-Ring Test Program & Abstracts:107-108,2004