Clinical Significance of the Measurement of Amount of Acetylcholine and the Frequency of Abnormal Cancer Reaction Positivity Using Bi-Digital O-Ring Test in the Respiratory Organs Diseases

Abstract

Purpose

We evaluate the usefulness of Bi-Digital O-Ring Test (ORT) originally developed by Omura, Y. in the diagnosis of the respiratory organs diseases, we have examined the frequency of cancer reaction positivity of ORT in various kinds of diseases and the amount of Acethylcholine of an abnormal part of each case measured.

Materials & Methods

101 patients were admitted with an abnormal shade in the chest X-ray photograph. Diagnosis was established with standard medical diagnostic methods including X-ray, bacteriology and pathological histology.

Distinguishing pre-cancer of cancer positive and negative cases by using the Bi-Digital ORing Test Method, we used Omura’s method of satisfying with following five conditions;

1) marked positive of Oncogene C -fos Ab2 2) marked positive of Integrin α ₅ β ₁ 2) marked positive of mercury 4) negative of very low Acethylcholine 5) strong positive viral infections. If a case satisfies these five conditions, we suppose that a case is cancer or pre-cancer. Preparing the sample in terms of the amount of Acetylcholine, the amount was established by using ORT.

Results

• ( 1 )

  25 cases of 25 lung cancer, cases all showed strong cancer positive responces, 24 cases of 26 viral pneumonia examples and 2 cases of 7 interstitial pneumonia, showed partial and weak positive responses to cancer.

• ( 2 )

  2 cases of viral pneumonia, 5 cases of interstitial pneumonia, 19 of bacterium infection, 4 of non-tuberculous pus in chest, 14 of tuberculous disease, 3 of old pneumonia, 3 of sarcoidosis; all these cases were negative of cancer parameters.

• ( 3 )

  An abnormal parts of body that shows Acetylcholine reaction positivity reacted with 500 μ g sample. The amount of the same substance of an abnormal area that shows Acetylcholine reaction negative distributed in a wide range from 1 μ g to 5 mg of the sample other than 500 μ g. The amount of Acethylcholine of confirment lung cancers were all very low and less than 50 μ g.

• ( 4 )

  There were many examples that the amount of Acetylcholine is decreasing with the improvement of the condition of disease in a convalescence file example of the infection of a lung. There were many examples that are increasing with the progress of the high value or, sickness and Acethylcholine gets at the truth of from a sickness early period in, a convalescene defective example.

Results and Conclusion

All examples of lung cancer showed cancer reaction strong positive. Many virus pneumonia and the part of interstitial pneumonia showed cancer reaction weak positive. This study indicates that one must consult the results of standard laboratory methods to make fine diagnosis, although ORT is very useful in screening of cancer. The amount of Acethylcholine is different by the extent of the strength of an inflammation in the infection of a lung. This result is suggesting that the measurement of the amount of Acetylcholine in an abnormal area of a lung infection is useful for the conjecture of the convalescene of an infection.