A computer program using fuzzy logic templates has been developed to enhance the diagnosis of malignant hyperpyrexia. When tested, retrospectively, against the physiological changes that occurred during the onset of a bona fide malignant hyperpyrexia episode it made the diagnosis about 10 minutes before the anaesthetist. When tested against the changes associated with laparoscopic surgery, which has certain similarities, the diagnosis of malignant hyperpyrexia was very transient. The use of this program may assist the anaesthetist in the diagnosis of this rare event.
OmbredanneL.De l'influence de l'anesthésique-employe dans la genise des accidents post-operatoire de paleur-hyperthermie observés chez les nourissons.Rev Med Fr1929; 10: 617.
2.
DenboroughM.A., LovellR.R.H.Anaesthetic deaths in a family.Lancet1960; 2: 45.
3.
JacksonP.Introduction to Expert Systems, Addison-Wesley Publishing Company, 1990.
4.
ShortliffeE.M.Computer based medical consulting: MYCIN project.Elsevier, New York.
5.
HudsonD.L., CohenM.E.Fuzzy Logic in Medical Expert Systems,IEEE Engineering in Medicine and Biology,1994; 13: 693–698.
6.
RamptonA.J., KellyD.A., ShanahanE.C., IngramG.S.Occurrence of malignant hyperpyrexia in a patient with osteogenesis imperfecta.Br J Anaesth1984; 56: 1443–1444.