Clinical Applications of Gaseous Nitric Oxide

Palmer R.M.J. , Ferrige A.G. , Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524–526.

Moncada S. , Palmer R.M.J. , Higgs E.A. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109–142.

Frostell C. , Fratacci M-D , Wain J.C. , Jones R. , Zapol W.M. Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation 1991; 83: 2038–2047.

Pepke-Zaba J. , Higenbottam T.W. , Dinh-Xuan A.T. , Stone D. , Wallwork J. Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet 1991; 338: 1173–1174.

Tibballs J. The role of nitric oxide (formerly endothelium-derived relaxing factor—EDRF) in vasodilatation and vasodilator therapy. Anaesth Intens Care 1993; 759–773.

Tibballs J. , Hochmann M. , Carter B. , Osborne A. An appraisal of techniques for administration of gaseous nitric oxide. Anaesth Intens Care 1993; 21: 844–847.

Rivera R.A. , Butt W. , Shann F. Predictors of mortality in children with respiratory failure: possible indications for ECMO. Anaesth Intens Care 1990; 18: 385–389.

Kinsella J.P. , Toews W.H. , Henry D. , Abman S.H. Selective and sustained pulmonary vasodilation with inhalational nitric oxide therapy in a child with idiopathic pulmonary hypertension. J Pediatr 1993; 122: 803–6.

Rossaint R. , Falke K.J. , Lopez F. , Slama K. , Pison U. , Zapol W.M. Inhaled nitric oxide for the adult respiratory distress syndrome. NEJM 1993; 328: 399–405.

Bigatello L.M. , Husford W.E. , Kacmarek R.M. , Roberts J.D. Jr. , Zapol W.M. Inhaled nitric oxide is a selective pulmonary vasodilator in septic patients with severe ARDS. Am Rev Respir Dis 1992; 145: A185.

Fratacci M.D. , Defouilley C. , Andrivet P. Responses to infusion of acetylcholine and inhalation of nitric oxide in patients with chronic obstructive lung disease and pulmonary hypertension. Am Rev Respir Dis 1992; 145: A722.

Roberts J.D. , Polaner D.M. , Land P. , Zapol W.M. Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 1992; 340: 818–19.

Kinsella J.P. , Neish S.R. , Shaffer E. , Abman S.H. Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 1992; 340: 819–20.

Roberts J.D. , Lang P. , Bigatello L.M. , Vlahakes G.J. , Zapol W.M. Inhaled nitric oxide in congenital heart disease. Circulation 1993; 87: 447–453.

Haydar A. , Malhere T. , Mauriat P. Inhaled nitric oxide for postoperative pulmonary hypertension in patients with congenital heart defects. Lancet 1992; 340: 1545.

Berner M. , Beghetti M. , Ricou B. , Rouge J.C. , Pretre R. , Friedli B. Relief of severe pulmonary hypertension after closure of a large ventricular septal defect using low dose inhaled nitric oxide. Intens Care Med 1993; 19: 75–77.

Foubert L. , Fleming B. , Latimer R. Safety guidelines for use of nitric oxide. Lancet 1992; 399: 1615–16.

Bouchet M. , Renaudin M-H , Raveau C. , Mercier J-C , Dehan M. , Zupan V. Safety requirements for use of inhaled nitric oxide in neonates. Lancet 1993; 341: 968–89.

Laguenie G. , Berg A. , Saint-Maurice J-P , Dinh-Xuan A.T. Measurement of nitrogen dioxide formation from nitric oxide by chemiluminescence in ventilated children. Lancet 1993; 341: 969.

Davidson D. NO bandwagon, Yes. Am Rev Respir Dis 1993; 147: 1078–79.