Alfentanil was used as an adjuvant to midazolam for analgesia in thirty outpatients undergoing colonoscopy. A similar group of thirty outpatients received fentanyl. The operating conditions and recovery times of the two groups were compared. Alfentanil usage resulted in better operating conditions. Recovery time was similar. Patient acceptance was high. No patient suffered respiratory depression during or after the procedure.
KawarP., PorterK.G., HunterE.K., McLaughlinJ., DundeeJ.W., BrophyT.Midazolam for upper gastrointestinal endoscopy. Ann R Coll Surg Engl1984; 66: 283–285.
2.
MilliganK.R., HoweJ.P., McLoughlinJ.Holmes W, Dundee J. Midazolam sedation for outpatient fibre optic endoscopy: evaluation of alfentanil supplementation. Ann R Coll Surg Engl1988; 70: 304–306.
3.
NiemegeersC.J.E., JanssenP.A.J.Alfentanil, a particularly short-acting intravenous narcotic analgesic. Drug Development and Research1981; 1: 83–88.
BovillJ.G., SebelP.S., BlackburnC.L., HeykantsJ.The pharmacokinetics of alfentanil — A new opioid analgesic. Anesthesiology1982; 57: 439–443.
6.
WhiteP.F., CoeV., ShaferA., SungM-L. Comparison of alfentanil with fentanyl for outpatient anesthesia. Anesthesiology1986; 64: 99–106.
7.
KayB., StephensonD.K.Alfentanil (R39209): initial clinical experience with a new narcotic analgesic. Anaesthesia1980; 35: 1197–1201.
8.
HullC.J., JacobsonL.A clinical trial of alfentanil as an adjuvant for short anaesthetic procedures. Br J Anaesth1983; 55: 173–178S.
9.
CollinsK.M., PlantevinO.M.Use of alfentanil in short anaesthetic procedures. JR Soc Med1985; 78: 456–458.
10.
CooperG.M., O'ConnorM., MarkJ., HarveyJ.Effect of alfentanil and fentanyl on recovery from brief anaesthesia. Br J Anaesth1983; 55: 179S–182S.
11.
KennedyD.J., OggT.W.Alfentanil and memory function. Anaesthesia1985; 40: 537–540.
12.
AntoniosW.R.A., InglisM.D., LeesN.W.Alfentanil in minor gynaecological surgery: use with etomidate and a comparison with halothane. Anaesthesia1984; 39: 812–815.
13.
EnwrightA.B., ParkerJ.B.R.Double-blind comparison of alfentanil N2O and fentanyl N2O for outpatient surgical procedures. Can J Anaesth1988; 35: 5: 462–467.
14.
KayB., VenkataramanP.Recovery after fentanyl and alfentanil in anaesthesia for minor surgery. Br J Anaesth1983; 55: 169S–171S.
