Abstract
In disease states, loss of homeostatic control may be countered by the provision of external inputs or therapy. Where the variables of interest may change rapidly and respond predictably to therapy, a patient/computer interface may be used to enhance data collection and/or in the formation of appropriate therapeutic responses. Ultimately, if appropriate dynamic responses are achieved, the patient therapy loop may be closed. Realisation of problem-free interfaces requires careful design of input transducers, computing hardware and software, output therapeutic devices and their integration. This process will require ingenuity, engineering competence and a thorough understanding of medicine and the clinical environment. In addition to sound technological solutions, the designer must be cognisant of the human aspects, for both patient and user of interface operation.