The prophylactic efficacy of pre-operative antacid administration was shown by comparing the pH and volumes of gastric contents in 50 female patients treated with 10 ml of Mist. Magnesium Trisilicate B.P.C. with that of 50 controls. Routine antacid prophylaxis was advocated for all patients undergoing pelvic laparoscopy as intra-operative conditions increase the risk of pulmonary acid aspiration.
References
1.
BannisterW. K., and SattilaroA. J. (1962): “Vomiting and Aspiration during Anaesthesia”, Anesthesiology, 23, 251
2.
ChristensenV., and SkovstedP. (1975): “Effects of General Anaesthetics on the pH of Gastric Contents in Man during Surgery”, Acta, Anaesth. Scand., 19, 49.
3.
CrawfordJ. S. (1970): “The Anaesthetist's Contribution to Maternal Mortality”, Brit. J. Anaesth., 42, 70.
4.
GrossmanM. I. (1962): “Current Gastroenterology”, Paul, B. Hoeber, Inc., p. 303.
5.
HesterJ. B., and HeathM. L. (1977): “Pulmonary Acid Aspiration Syndrome: Should Prophylaxis be Routine?”, Brit. J. Anaesth., 49, 595.
6.
HutchinsonB. R., and NewsonA. J. (1975): “Preoperative Neutralization of Gastric Acidity”, Anaesth. Intens Care, 3, 198.
7.
IsenbergC. L. (1975): “Therapy of Peptic Ulcer”, J. Amer. Med. Ass., 233, 540.
8.
MendelsonC. L. (1946): “The Aspiration of Stomach Contents into the Lungs during Obstetric Anaesthesia”, Amer. J. Ohstet. Gynec., 52, 191.
9.
NewsonA. J. (1977): “The Effectiveness and Duration of Pre-operative Antacid Therapy”, Anaesth. Intens. Care, 5, 214.
10.
PeskettW. G. H. (1973): “Antacids before Obstetric Anaesthesia”, Anaesthesia.28, 509.
11.
RobertsR. B., and ShirleyM. A. (1974): “Reducing the Risk of Acid Aspiration during Caesarean Section”. Anaesth. Analg. Curr. Res., 53, 859.
12.
TaylorG., and Pryse-DaviesJ. (1966): “The Prophylactic Use of Antacids in the Prevention of the Acid Pulmonary Aspiration Syndrome (Mendelson's Syndrome)”. Lancet.1, 288.
13.
TaylorG. (1975a): “Acid Pulmonary Aspiration Syndrome after Antacids: Case Report”, Brit. J. Anaesth., 47, 615.
