A case history is presented of a woman who developed very severe bronchospasm, hypotension, “lobster-red “erythema and later angio edema of the head and neck after induction of anaesthesia for caesarean section. Intradermal testing at a later date, showed immediate-type sensitivity to suxamethonium. Reference is made to the other few reactions to suxamethonium reported in the world literature.
References
1.
AustenK. F. (1974): “Introduction to Clinical Immunology”, Harrison's Principles of Internal Medicine—7th ed.—pp. 346–7. Saunders. London.
2.
Bele-BindaN., and ValeriF. (1971): “A Case of Bronchospasm Induced by Succinylcholine”, Canad. Anaesth. Soc. J., 18, 116.
3.
BournsJ. G., CollierH. C. J., and SommersG. F. (1952): “Succinylcholine Muscle Relaxant of Short Duration”, Lancet, 1, 1225.
4.
BovetD.et al (1949): “Proprieta Farmacodinamiche di Alcun Derivati della Succinilcolina Dotati di Azione Curarica”, Rendic 1st super san, 12, 106–137.
FelliniA. A., BernsteinR. L., and ZauderH. L. (1963): “Bronchospasm due to Suxamethonium”, Report of a Case, Brit. J. Anaesth., 35, 657.
7.
FisherM. McD. (1975): “Severe Histamine Mediated Reactions to Intravenous Drugs in Anaesthesia”, Anaesth. Intens. Care, 3, 180.
8.
HuntR., Taveaude M. (1911): “Effects of Number of Derivatives of Choline and Analogous Compounds on Blood Pressure”, U.S. Hygienic Laboratory Bulletin73, Washington D.C.
9.
JerumsG., WhittinghamJ., and WilsonP. (1967): “Anaphylaxis to Suxamethonium: A Case Report”, Brit. J. Anaesth., 39, 73.
10.
KatzA. M., and MulliganP. G. (1972): “Case Report: Bronchospasm Induced by Suxamethonium”, Brit. J. Anaesth., 44, 1097.
11.
KepesE. R., and HaimoviciH. (1959): “Allergic Reaction to Succinylcholine”, J. Amer. Med. Ass., 171, 548.
12.
LeeJ. A., and AtkinsonR. S. (1973): Synopsis of Anaesthesia, 7th ed—Chapter XXXII, Wright & Sons, Bristol.