The use of physostigmine in the treatment of tricyclic antidepressant overdose is discussed. The importance of continuous observation is emphasized and the method of preparation of physostigmine is outlined.
References
1.
BernardsW. (1973): “Reversal of Phenothiazine Induced Coma with Physostigmine”, Anesth. Analg. Curr. Res., 52, 938.
2.
BurkeJ. S., WalkerJ. E., ReimockB. H., and OttJ. E. (1974): “Tricyclic Antidepressant Poisoning. Reversal of Coma, Choreoathetosis and Myoclonus by Physostigmine”, J. Amer. Med. Ass., 230, 1405.
3.
DuvoisinR. C., and KatzR. (1908): “Reversal of Central Anticholinergic Syndrome in Man by Physostigmine”, J. Amer. Med. Ass., 206, 1963.
4.
GoodmanL. S., and GillmanA. (1970): Pharmacological Basis of Therapeutics.Macmillan, New York.
5.
GreeneL. T. (1971): “Physostigmine Treatment of Anticholinergic Drug Depression in Post-operative Patients”, Anesth. Analg., 50, 222.
6.
HeiserJ. F., and GillinJ. C. (1971): “The Reversal of Anticholinergic Drug Induced Delirium and Coma with Physostigmine”, Am. J. of Psychiatry, 127, 1050.
7.
HeiserJ. F., and WilbertD. E. (1974): “Reversal of Delirium Induced by Tricyclic Antidepressant Drugs with Physostigmine”, Amer. J. Psychiatry, 131, 1275.
8.
SlovisT. L., OttJ. E., and TeitelbaumD. T. (1971): “Physostigmine Therapy in Acute Tricyclic Antidepressant Poisoning”, Clin. Toxicol., 4, 451.
9.
SnyderB. D., BlondeL., and McWhirterW. R. (1974): “Reversal of Amitriptyline Intoxication by Physostigmine”, J. Amer. Med. Ass., 230, 1433.
