The case history of a patient with severe cardiac arrhythmias following overdose with thioridazine is reported. Management is outlined and discussed.
References
1.
AlexanderC. S., and NinoA. (1969): “Cardiovascular Complications in Young Patients Taking Psychotropic Drugs”, Amer. Heart J., 78, 757.
2.
BanT. A., and St. JeanA. (1964): “The Effect of Phenothiazines on the Electrocardiogram”, Can. Med. Ass. J., 91, 537.
3.
BrownT. C. K., BarkerG. A., DunlopM. E., and LoughnanP. M. (1973): “The Use of Sodium Bicarbonate in the Treatment of Tricyclic Anti-depressant-induced arrhythmias”, Anaesth. Intens. Care, 1, 203.
4.
BurdaG. E. (1968): “Electrocardiographic abnormalities Induced by Thioridazine”, Amer. Heart J., 76, 153.
5.
DesautelsS., FilteauC., and St. JeanA. (1964): “Ventricular Tachycardia Associated with Administration of Thioridazine Hydrochloride (Mellaril)”, Can. Med. Ass. J., 90, 1030.
6.
GilesT. D., and ModlinR. K. (1968): “Death Associated with Ventricular Arrhythmia and Thioridazine Hydrochloride”, J. Amer. Med. Ass., 205, 98.
7.
HollisterL. E., and KosekJ. C. (1965): “Sudden Death During Treatment with Phenothiazine Derivatives”, J. Amer. Med. Ass., 192, 1035.
8.
HustonJ. R., and BellG. E. (1966): “The Effect of Thioridazine Hydrochloride and Chlorpromazine on the Electrocardiogram”, J. Amer. Med. Ass., 198, 134.
9.
KellyH. G., FayJ. E., and LavertyS. G. (1963): “Thioridazine Hydrochloride (Mellaril): Its Effect on the Electrocardiogram and a Report of Two Fatalities with Electrocardiographic Abnormalities”, Can. Med. Ass. J., 89, 546.
10.
LeestmaJ. E., and KoeningK. L. (1938): “Sudden Death and Phenothiazines. A Current Controversy”, Arch. Gen. Psychiat., 18, 137.
