We report a case where a patient presented with generalised tonic-clonic seizures secondary to nausea, vomiting and dehydration. She had suffered a postpartum haemorrhage six months previously. On laboratory assessment hyponatraemia and low hormone concentrations suggested pituitary failure. The diagnosis was confirmed by magnetic resonance imaging of the head, which showed a partially empty sella turcica. Given the severity of the morbidity in this case we emphasise that Sheehan's syndrome should be suspected in women presenting with postpartum seizures.
RobertsD.M.Sheehan's syndrome.American Family Physician1988; 37: 223–227.
5.
KageyamaY., HiroseS., TerashiK., NakayamaS., KomatsuzakiO., FukudaH.A case of postpartum hypopituitarism (Sheehan's syndrome) associated with severe hyponatremia and congestive heart failure.Jpn J Med1988; 27: 337–341.
6.
De GrootL.J.In: Textbook of Endocrinology,2nd ed.Philadelphia, Pennsylvania: WB Saunders Company1989. p. 431–432.
7.
DanN.G., FeinerR.I.D., HouangM.T.W., TurnerJ.J.Pituitary apoplexy in association with lymphocytic hypophysitis.J Clin Neurosci2002; 9: 577–580.
8.
LambertsS.W., de HerderW.W., van der LelyA.J.Pituitary insufficiency.Lancet1998; 352: 127–134.
AnfusoS., PatrelliT.S., SonciniE., ChioderaP., FaddaG.M., NardelliG.B.A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia.Acta Biomed2009; 80: 73–76.
11.
DaviesJ.S., ObuobieK., SmithJ., ReesD.A., FurlongA., DaviesN.A therapeutic trial of growth hormone in hypopituitary adults and its influence upon continued prescription by general practitioners.Clin Endocrinol (Oxf)2000; 52: 295–303.