We present four patients in whom a “ketofol” (ketamine 200 mg and propofol 200 mg) infusion was used in conjunction with regional anaesthesia. The patients were considered ‘high risk’ due to their medical condition or age. The ketofol proved safe and effective in all four cases. Advantages of this technique included analgesia, airway preservation, maintenance of spontaneous respiration, haemodynamic stability and rapid recovery.
VisserE., SchugS.A.The role of ketamine in pain management. Biomed Pharmacother2006; 60: 341–348.
2.
WillmanE.V., AndolfattoG.A prospective evaluation of ‘ketofol’ (ketamine/propofol combination) for procedural sedation and analgesia in the emergency department. Ann Emerg Med2007; 49: 23–30.
3.
BoteroC.A., SmithC.E., HolbrookC., ChavezA.M., SnowN.J., HagenJ.F.Total intravenous anesthesia with a propofol-ketamine combination during coronary artery surgery. J Cardiothorac Vase Anesth2000; 14: 409–415.
4.
LahteenmakiM., SaloM., TenovuoJ.Mucosal host defence response to hysterectomy assessed by saliva analysis: a comparison of propofol and isoflurane anaesthesia. Anaesthesia1998; 53: 1067–1073.
5.
TrisselL.A., GilbertD.L., MartinezJ.F.Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration. Am J Health-Syst Pharm1997; 54: 1287–1292.
6.
AoudM.T., MoussaA.R., DagherC.M., MuwakkitS.A., Jabbour-KhouryS.I., ZbeidyR.A.Addition of ketamine to propofol for initiation of procedural anesthesia in children reduces propofol consumption and preserves hemodynamic stability. Acta Anaesthesiol Scand2008; 52: 561–565.
7.
PaixB.R., CappsR., NeumeisterG., SempleT.Anaesthesia in a disaster zone: a report on the experience of an Australian medical team in Banda Aceh following the “Boxing Day Tkunami”. Anaesth Intensive Care2005; 33: 629–634.