Two case reports of nonepileptic children are presented, who developed paroxysmal EEG potentials in routinely performed EEG recordings during inhalation of sevoflurane, 7 and 8% by volume respectively. Taking into account several reports from the literature about epileptiform potentials or convulsive movements under similar conditions, it seems to be important to investigate carefully the circumstances under which these phenomena appear as well as possible clinical consequences.
HobbhahnJ., FunkW.Sevofluran in der Kinderanästhesie.Anaesthetist1996; 45(Suppl 1): S22–S27.
2.
HobbhahnJ., SchwallB., HoeraufK.. Inhalative Einleitung mit Sevofluran bei Erwarchsenen—Effektivität, Sicherheit, Patientenakzeptanz und Arbeitsplatzkonzentrationen.Anaes-thesiol Intensivmed1998; 3: 118–124.
3.
O'BrienK., KumarR., MortonN.S.Sevoflurane compared with halothane for tracheal intubation in children.Br J Anaesth1998; 80: 452–455.
4.
JohannessonG.P., FlorenM., LindahlS.G.E.Sevoflurane for ENT-surgery in children. A comparison with halothane.Acta Anaesthesiol Scand1995; 39: 546–550.
5.
PiatV., DuboisM-C, JohanetS., MuratI.Induction and recovery characteristics and hemodynamic responses to sevoflurane and halothane in children.Anesth Analg1994; 79: 840–844.
6.
SarnerJ.B., LevineM., DavisP.J., LermanJ., CookR., MotoyamaE.K.Clinical characteristics of sevoflurane in children.Anesthesiology1995; 82: 38–46.
7.
SchultzA., SchultzB., GrouvenU., BokelmannB., KitzkiT.Narcotrend—EEG-Monitor für OP und Intensivstation. Dtsch.Ärzteblatt1999; 96: B-1244–B-1255.
8.
WoodforthI.J., HicksR.G., CrawfordM.R., StephenJ.P.H., BurkeD.J.Electroencephalographic evidence of seizure activity under deep sevoflurane anesthesia in a nonepileptic patient.Anesthesiology1997; 87: 1579–1582.
9.
KomatsuH., TaieS., EndoS., FukudaK., UekiM., NogayaJ., OgliK.Electrical seizures during sevoflurane anesthesia in two pediatric patients with epilepsy.Anesthesiology1994; 81: 1535–1537.
10.
HagaS., ShimaT., MomoseK., AndohK., HashimotoY.Anesthetic induction of children with high concentrations of sevoflu-rane.Masui1992; 41: 1951–1955.
11.
ZachariasM.Convulsive movements with sevoflurane in children.Anaesth Intensive Care1997; 25: 727.
