A retrospective study of cecal and colonic tissues from 28 squirrel monkeys (Saimiri sciureus and Saimiri boliviensis) demonstrated enteric trichomonads within luminal Crypts. Twenty-One of 28 (75%) had trichomonads in the mucosal epithelium either in cup-like depressions or intraepithelial vacuoles. Organisms were also beneath the superficial luminal mucosal epithelium and between the basement membrane and crypt epitheial cells. Immunoperoxidase staining also identified organisms within the lamina propria and submucosa. Additional histologic changes included mucosal ulceration, multifocal cryptitis, and focal epithelial necrosis. Most areas containing trichomonads did not have an associated inflammatory response.
References
1.
BlanchardJLBaskinGB:
Trichomonas gastritis in Rhesus monkeys infected with the simian immunodeficiency virus.
J Infect Dis157:
1092–1093,
1988
2.
BradyAGPindakFFAbeeCRGardnerWA:
Enteric trichomonads of squirrel monkeys (Saimiri sp.): natural infestation and treatment.
Am J Primatol14:
65–71,
1988
3.
BuntonTELowenstineLJLeiningerR:
Invasive trichomoniasis in a Callicebus moloch.
Vet Pathol20:
491–494,
1983
4.
CulbersonDEPindakFFGardnerWAHonigbergBM:
Tritrichomonas mobilensis n. sp. (Zoomastigophorea: Trichomonadida) from the Bolivian squirrel monkey Saimiri boliviensis boliviensis.
J Protozool33
(2):
301-304,
1986
5.
CulbersonDEScimecaJMGardnerWAAbeeCR:
Pathogenicity of Tritrichomonas mobilensis: subcutaneous inoculation in mice.
J Parasitol74
(5):
774–780,
1988
6.
EtzlerME:
Lectin receptors on the intestinal cell surface.
In:
Attachment of Organisms to the Gut Mucosa,
BoedekerEC,
vol. 2,
pp. 148–155.
CRC Press,
Boca Raton,
1984
7.
FitzgeraldPR:
Bovine trichomoniasis.
In:
Veterinary Clinics of North America, Food Animal Practice.
vol. 2,
pp. 277–282.
WB Saunders,
Philadelphia,
1986
8.
FrostJKHonigbergBM:
Comparative pathogenicity of Trichomonas vaginalis and Trichomonas gallinae to mice. II. Histopathology of subcutaneous lesions.
J Parasitol48
(6):
898–918,
1962
9.
GardnerWACulbersonDEScimecaJMBradyAGPindakFFAbeeCR:
Experimental genital trichomoniasis in the squirrel monkey (Saimiri sciureus).
Genitourin Med63:
188–191,
1987
10.
HonigbergBMGuptaPKSpenceMRFrostJKKuczynskaKChoromanskiLWartonA:
Pathogenicity of Trichomonas vaginalis: cytopathologic and histopathologic changes of the cervical epithelium.
Obstet Gynecol64:
179–184,
1984
LevineND:
Veterinary Protozology,
pp. 59–88.
Iowa State University Press,
Ames,
1985
13.
MigakiGBenirschkeKMcKeeAECaseyHW:
Trichomonal granuloma of the pelvic cavity in a Rhesus monkey.
Vet Pathol15:
679–681,
1978
14.
Perez MesaCStablerRM:
Histopathological changes in the domestic pigeon infected with Trichomonas gallinae (Jones' Barn strain).
Avian Dis5:
48–59,
1961
15.
PindakFFGardnerWAPindakM:
Detection of hemagglutinins in cultures of squirrel monkey intestinal trichomonads.
J Clin Microbiol25:
609–614,
1987
16.
PindakFFPindakM:
Detection and cultivation of intestinal trichomonads of squirrel monkeys (Saimiri sciureus).
Am J Primatol9:
197–205,
1985
17.
RhyanJCStackhouseLLQuinnWJ:
Fetal and placental lesions in bovine abortion due to Tritrichomonas foetus.
Vet Pathol25:
350–355,
1988
18.
SunT:
Trichomoniasis.
In:
Pathology and Clinical Features of Parasitic Diseases, Masson Monographs in Diagnostic Pathology,
SunT,
pp. 89–94.
Masson Publishing USA,
New York,
1982
19.
Van KruiningenHJ:
Gastrointestinal system,
In:
Special Veterinary Pathology,
ThompsonRG,
pp. 143–144.
Decker Inc,
Philadelphia,
1988
20.
WellsDJDemesPPindakFFPindakM:
Sialic acid specific lectin from parasitic Tritrichomonads.
Abstracts of the American Society for Microbiology Annual Meeting,
p. 60,
1988
