Cutaneous lesions of 36 collie dogs affected with dermatomyositis were reviewed. The most common histologic features were follicular atrophy and perifollicular inflammation in 30 dogs, which correlated with alopecia clinically. Other less common findings included formation of colloid bodies, basal cell vacuolation, and subepidermal vesiculation. Results indicated that the most diagnostic cutaneous histologic features of dermatomyositis may be follicular atrophy and inflammation.
References
1.
BohanAPeterJB:
Polymyositis and dermatomyositis.New Engl J Med292:
403,
1975
2.
ConroyJD:
The etiology and pathogenesis of alopecia.Comp Contin Educ Pract Vet8:
806,
1979
3.
EverettMACurtisAC:
Dermatomyositis.Arch Int Med100:
70,
1957
HargisAMHauptKHPrieurDJMooreMP:
A skin disorder in three Shetland sheepdogs: comparison with familial canine dermatomyositis of collies.Comp Contin Educ Pract Vet7:
306,
1985
6.
HauptKHPrieurDJMooreMPHargisAMHegrebergGAGavinPRJohnsonRS:
Familial canine dermatomyositis: clinical, electrodiagnostic and genetic studies.Am J Vet Res46:
1861,
1985
7.
JanisJFWinklemanRK:
Histopathology of the skin in dermatomyositis.Arch Dermatol97:
640,
1968
8.
KrainLS:
Dermatomyositis in six patients without initial muscle involvement.Arch Dermatol111:
241,
1975
