A 10.25-year-old female beagle had an invasive neoplasm at the base of the heart which metastasized to the lungs, pancreas, and kidney. The neoplasm in these locations was composed of clusters of polyhedral cells surrounded by fine fibrovascular stroma. The differential diagnoses were malignant chemodectoma, ectopic parathyroid carcinoma, and ectopic thyroid carcinoma. Based on ultrastructural features, this tumor was an ectopic thyroid carcinoma.
References
1.
AngletonG.M.LoPrestiC.A.:
A summary of the dosimetrics for exposures to 60Co of the beagles entered into the CRHL long-term study.
Health Phys33:
100–103,
1977.
2.
CapenC.C.:
Tumors of the chemoreceptor organs. In:
Tumors in Domestic Animals,
ed. MoultonJ.E.,
pp. 414–420,
2nd ed.University of California Press, Berkeley,
1978.
3.
ChevilleN.F.:
Ultrastructure of canine carotid body and aortic body tumors.
Vet Pathol9:
166–189,
1972.
4.
JohnsonK.H.:
Aortic body tumors in the dog.
J Am Vet Med Assoc152:
154–160,
1968.
5.
JubbK.V.F.KennedyP.C.:
Tumors of the nonchromaffin paraganglia in dogs.
Cancer10:
89–99,
1957.
6.
MontgomeryD.L.BendeleR.StortsR.W.:
Malignant aortic body tumor with metastasis to bone in a dog.
Vet Pathol17:
241–244,
1980.
PatnaikA.K.MacEwenE.G.ErlandsonR.A.LiebermanP.H.LiuS.K.:
Mediastinal parathyroid adenocarcinoma in a dog.
Vet Pathol15:
55–63,
1978.
9.
SmithcorsJ.F.:
Accessory thyroid tissue. In:
Anatomy of the Dog,
ed. MillerChristensenEvans,
pp. 820–821.
W. B. Saunders, Philadelphia,
1965.
10.
SzczechG.M.BlevinsW.E.CarltonW.W.CutlanG.R.:
Chemodectoma with metastasis to bone in a dog.
J Am Vet Med Assoc16:
376–378,
1973.
11.
ThakeD.C.ChevilleN.F.SharpR.K.:
Ectopic thyroid adenomas at the heart base of the dog. Ultrastructural identification of dense tubular structures within endoplasmic reticulum.
Vet Pathol8:
421–432,
1971.
